用氨基羟丙基二膦酸盐治疗甲状腺毒症中的高钙血症。
Treatment of hypercalcaemia in thyrotoxicosis with aminohydroxypropylidene diphosphonate.
作者信息
Tan T T, Alzaid A A, Sutcliffe N, Gardner M D, Thomson J A, Boyle I T
机构信息
University Department of Medicine, Royal Infirmary, Glasgow, UK.
出版信息
Postgrad Med J. 1988 Mar;64(749):224-7. doi: 10.1136/pgmj.64.749.224.
Abstract
Two patients had symptomatic hypercalcaemia accompanying thyrotoxicosis, despite initial treatment with volume repletion, beta blockade and antithyroid drugs. They were further managed with intravenous infusions of aminohydroxypropylidene diphosphonate resulting in rapid normalization of the serum calcium, with relief of symptoms. Aminohydroxypropylidene diphosphonate effectively suppressed the increased bone resorption of thyrotoxicosis without any undesirable adverse effects.
摘要
两名患者在伴有甲状腺毒症的情况下出现了症状性高钙血症，尽管最初采用了补液、β受体阻滞剂和抗甲状腺药物治疗。他们进一步接受了静脉输注氨羟丙基二膦酸盐治疗，血清钙迅速恢复正常，症状得到缓解。氨羟丙基二膦酸盐有效地抑制了甲状腺毒症时增加的骨吸收，且无任何不良副作用。
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Effect of single high dose infusions of aminohydroxypropylidene diphosphonate on hypercalcaemia caused by cancer.单次大剂量输注氨羟丙基二膦酸盐对癌症所致高钙血症的影响。
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9
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