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剂量计算器(DoseCal):一款用于人和不同动物物种之间剂量转换的虚拟计算器。

DoseCal: a virtual calculator for dosage conversion between human and different animal species.

作者信息

Janhavi P, Divyashree S, Sanjailal K P, Muthukumar S P

机构信息

Department of Biochemistry, CSIR Central Food Technological Research Institute, Mysore, India.

Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.

出版信息

Arch Physiol Biochem. 2022 Apr;128(2):426-430. doi: 10.1080/13813455.2019.1687523. Epub 2019 Nov 20.

Abstract

CONTEXT

The scientists as well as pharmacologists frequently convert the dose of drugs or extracts between human and different animal species. According to the literature, the extrapolation of the dose by simple conversion based only on body weight is not an accurate method. The miscalculation of dosage conversion may result in adverse effects due to overdose or reduced potency due to underdose.

AIM

To develop a conversion calculator with factual factor like factor.

METHOD

The virtual calculator was developed as a web-based application using hypertext pre-processor programming language. My SQL software was used to store the data related to DoseCal.

RESULTS

Based on the factor, dose conversion calculator called DoseCal was developed. The DoseCal would provide the dosage for both per kg and actual weight of the animal taken for the experiment.

CONCLUSION

The DoseCal would assist scientists in the dosage conversion easily and accurately between species.

摘要

背景

科学家和药理学家经常在人类和不同动物物种之间转换药物或提取物的剂量。根据文献,仅基于体重进行简单转换来推算剂量并非准确方法。剂量转换计算错误可能因用药过量导致不良反应,或因用药不足导致药效降低。

目的

开发一种具有如 因子等实际因素的转换计算器。

方法

使用超文本预处理器编程语言将虚拟计算器开发为基于网络的应用程序。使用MySQL软件存储与剂量计算器(DoseCal)相关的数据。

结果

基于 因子,开发了名为剂量计算器(DoseCal)的剂量转换计算器。DoseCal将提供实验所用动物每千克体重和实际体重的剂量。

结论

DoseCal将帮助科学家轻松、准确地在不同物种之间进行剂量转换。

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