van Markus-Doornbosch Frederike, van der Holst Menno, de Kloet Arend J, Vliet Vlieland Thea P M, Meesters Jorit J L
Basalt Rehabilitation , The Hague, The Netherlands.
Leiden University Medical Center , Leiden, The Netherlands.
Dev Neurorehabil. 2020 Jul;23(5):328-335. doi: 10.1080/17518423.2019.1692948. Epub 2019 Nov 20.
To study the association between fatigue and participation and QoL after acquired brain injury (ABI) in adolescents and young adults (AYAs).
MATERIALS & METHODS: Cross-sectional study with AYAs aged 14-25 years, diagnosed with ABI. The PedsQL™ Multidimensional Fatigue Scale, Child & Adolescent Scale of Participation, and PedsQL™4.0 Generic Core Scales were administered.
Sixty-four AYAs participated in the study, 47 with traumatic brain injury (TBI). Median age at admission was 17.6 yrs, 0.8 yrs since injury. High levels of fatigue (median 44.4 (IQR 34.7, 59.7)), limited participation (median 82.5 (IQR 68.8, 92.3)), and diminished QoL (median 63.0 (IQR 47.8, 78.3)) were reported. More fatigue was significantly associated with more participation restrictions (β 0.64, 95%CI 0.44, 0.85) and diminished QoL (β 0.87, 95%CI 0.72, 1.02).
AYAs with ABI reported high levels of fatigue, limited participation and diminished quality of life with a significant association between fatigue and both participation and QoL. Targeting fatigue in rehabilitation treatment could potentially improve participation and QoL.
研究青少年和青年成人（AYAs）获得性脑损伤（ABI）后疲劳与参与度及生活质量（QoL）之间的关联。
对年龄在14 - 25岁、被诊断为ABI的AYAs进行横断面研究。采用儿童生活质量量表（PedsQL™）多维疲劳量表、儿童与青少年参与度量表以及儿童生活质量量表（PedsQL™）4.0通用核心量表进行评估。
64名AYAs参与了该研究，其中47名患有创伤性脑损伤（TBI）。入院时的中位年龄为17.6岁，受伤后0.8年。报告显示存在高水平的疲劳（中位数44.4（四分位间距34.7，59.7））、有限的参与度（中位数82.5（四分位间距68.8，92.3））以及生活质量下降（中位数63.0（四分位间距47.8，78.3））。更多的疲劳与更多的参与限制（β 0.64，95%置信区间0.44，0.85）以及生活质量下降（β 0.87，95%置信区间0.72，1.02）显著相关。
患有ABI的AYAs报告称存在高水平的疲劳、有限的参与度以及生活质量下降，且疲劳与参与度及生活质量之间存在显著关联。在康复治疗中针对疲劳可能会潜在地改善参与度和生活质量。
