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火器伤幸存者的长期功能、心理、情感及社会结局

Long-term Functional, Psychological, Emotional, and Social Outcomes in Survivors of Firearm Injuries.

作者信息

Vella Michael A, Warshauer Alexander, Tortorello Gabriella, Fernandez-Moure Joseph, Giacolone Joseph, Chen Bofeng, Cabulong Alexander, Chreiman Kristen, Sims Carrie, Schwab C William, Reilly Patrick M, Lane-Fall Meghan, Seamon Mark J

机构信息

Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

currently affiliated with Division of Acute Care Surgery and Trauma, University of Rochester Medical Center, Rochester, New York.

出版信息

JAMA Surg. 2020 Jan 1;155(1):51-59. doi: 10.1001/jamasurg.2019.4533.

Abstract

IMPORTANCE

The outcomes of firearm injuries in the United States are devastating. Although firearm mortality and costs have been investigated, the long-term outcomes after surviving a gunshot wound (GSW) remain unstudied.

OBJECTIVE

To determine the long-term functional, psychological, emotional, and social outcomes among survivors of firearm injuries.

DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study assessed patient-reported outcomes among GSW survivors from January 1, 2008, through December 31, 2017, at a single urban level I trauma center. Attempts were made to contact all adult patients (aged ≥18 years) discharged alive during the study period. A total of 3088 patients were identified; 516 (16.7%) who died during hospitalization and 45 (1.5%) who died after discharge were excluded. Telephone contact was made with 263 (10.4%) of the remaining patients, and 80 (30.4%) declined study participation. The final study sample consisted of 183 participants. Data were analyzed from June 1, 2018, through June 20, 2019.

EXPOSURES

A GSW sustained from January 1, 2008, through December 31, 2017.

MAIN OUTCOMES AND MEASURES

Scores on 8 Patient-Reported Outcomes Measurement Information System (PROMIS) instruments (Global Physical Health, Global Mental Health, Physical Function, Emotional Support, Ability to Participate in Social Roles and Activities, Pain Intensity, Alcohol Use, and Severity of Substance Use) and the Primary Care PTSD (posttraumatic stress disorder) Screen for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.

RESULTS

Of the 263 patients who survived a GSW and were contacted, 183 (69.6%) participated. Participants were more likely to be admitted to the hospital compared with those who declined (150 [82.0%] vs 54 [67.5%]; P = .01). Participants had a median time from GSW of 5.9 years (range, 4.7-8.1 years) and were primarily young (median age, 27 years [range, 21-36 years]), black (168 [91.8%]), male (169 [92.3%]), and employed before GSW (pre-GSW, 139 [76.0%]; post-GSW, 113 [62.1%]; decrease, 14.3%; P = .004). Combined alcohol and substance use increased by 13.2% (pre-GSW use, 56 [30.8%]; post-GSW use, 80 [44.0%]). Participants had mean (SD) scores below population norms (50 [10]) for Global Physical Health (45 [11]; P < .001), Global Mental Health (48 [11]; P = .03), and Physical Function (45 [12]; P < .001) PROMIS metrics. Eighty-nine participants (48.6%) had a positive screen for probable PTSD. Patients who required intensive care unit admission (n = 64) had worse mean (SD) Physical Function scores (42 [13] vs 46 [11]; P = .045) than those not requiring the intensive care unit. Survivors no more than 5 years after injury had greater PTSD risk (38 of 63 [60.3%] vs 51 of 119 [42.9%]; P = .03) but better mean (SD) Global Physical Health scores (47 [11] vs 43 [11]; P = .04) than those more than 5 years after injury.

CONCLUSIONS AND RELEVANCE

This study's results suggest that the lasting effects of firearm injury reach far beyond mortality and economic burden. Survivors of GSWs may have negative outcomes for years after injury. These findings suggest that early identification and initiation of long-term longitudinal care is paramount.

摘要

重要性

在美国,枪支伤害的后果是毁灭性的。尽管已经对枪支死亡率和成本进行了调查,但枪伤(GSW)幸存者的长期后果仍未得到研究。

目的

确定枪支伤害幸存者的长期功能、心理、情感和社会后果。

设计、地点和参与者:这项前瞻性队列研究评估了2008年1月1日至2017年12月31日期间,在一家城市一级创伤中心的枪伤幸存者中患者报告的结果。研究人员试图联系在研究期间存活出院的所有成年患者(年龄≥18岁)。共识别出3088名患者;排除了516名(16.7%)在住院期间死亡的患者和45名(1.5%)出院后死亡的患者。对其余患者中的263名(10.4%)进行了电话联系,其中80名(30.4%)拒绝参与研究。最终的研究样本包括183名参与者。数据分析时间为2018年6月1日至2019年6月20日。

暴露因素

2008年1月1日至2017年12月31日期间遭受的枪伤。

主要结局和测量指标

8项患者报告结局测量信息系统(PROMIS)工具的得分(全球身体健康、全球心理健康、身体功能、情感支持、参与社会角色和活动的能力、疼痛强度、酒精使用和物质使用严重程度)以及《精神疾病诊断与统计手册》第五版的初级保健创伤后应激障碍(PTSD)筛查。

结果

在263名枪伤幸存者中,183名(69.6%)参与了研究。与拒绝参与的患者相比,参与研究的患者更有可能入院(150名[82.0%]对54名[67.5%];P = 0.01)。参与者从枪伤到研究时的中位时间为5.9年(范围4.7 -

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