Alat I
Bratisl Lek Listy. 2019;120(11):827-831. doi: 10.4149/BLL_2019_137.
This study was aimed to reveal whether there is a relationship between Raynaud Phenomenon (RP) and Helicobacter Pylori (HP).
Seventy-nine patients, who had been referred to outpatient clinic with Raynaud in the last 9 years were retrospectively screened. Of these, 29 patients with access to their data and who had HP screening tests were included in the study.
HP direct antigen was found in feces in only one of 29 patients. When we compared the results of this study to the results of previous literature, it was observed that the patients admitted with RP symptoms by a gastroenterology outpatient clinic had a higher incidence for HP (+) scanning than the patients admitted with RP symptoms by a cardiovascular surgery policlinic (CVSOC).
Although previous literature reports that HP leads to RP in the group of patients referred to other outpatient clinics, the same relation is very low in the Raynaud patient group in CVSOC. Patients admitted with RP in the CVSOC shouldn't be prescribed empirical antibiotic therapy for the eradication of HP. However, as the appropriate antibiotic regimen can resolve Raynaud symptoms in the presence of a HP(+) test, it makes this scanning rational for all symptomatic patients (Tab. 1, Fig. 1, Ref. 23).
本研究旨在揭示雷诺现象（RP）与幽门螺杆菌（HP）之间是否存在关联。
回顾性筛查了过去9年因雷诺现象转诊至门诊的79例患者。其中，29例可获取其数据且进行了HP筛查试验的患者被纳入研究。
29例患者中仅1例粪便中发现HP直接抗原。当我们将本研究结果与先前文献结果进行比较时，发现消化内科门诊以RP症状收治的患者HP（+）扫描发生率高于心血管外科门诊（CVSOC）以RP症状收治的患者。
尽管先前文献报道在转诊至其他门诊的患者组中HP会导致RP，但在CVSOC的雷诺病患者组中这种关联非常低。CVSOC中以RP收治的患者不应为根除HP而给予经验性抗生素治疗。然而，由于合适的抗生素方案在HP（+）检测阳性时可缓解雷诺症状，因此对所有有症状的患者进行这种扫描是合理的（表1，图1，参考文献23）。
