一种用于测量大鼠伸舌的光纤光电管探测器：局部皮质损伤恢复情况的评估

An optic-fiber photocell detector for measuring tongue protrusion in the rat: evaluation of recovery from localized cortical lesions.

作者信息

Whishaw I Q, Tompkins G J

机构信息

Department of Psychology, University of Lethbridge, Alberta, Canada.

出版信息

Physiol Behav. 1988;43(3):397-401. doi: 10.1016/0031-9384(88)90205-3.

DOI:10.1016/0031-9384(88)90205-3

PMID:3174852

Abstract

A technique for measuring tongue protrusion during licking by rats is described. Liquid is automatically dispensed onto a shelf in front of the rats' cage. An array of 16 optic fibers spaced at 1 mm intervals act as photo detectors to measure tongue protrusion. The fibers activate relays connected to a microcomputer that counts individual beam breaks. The system permits the measurement of large numbers of consecutive tongue protrusions during training and testing of control and brain-damaged rats. It is shown that ventral frontal cortical lesions disrupt tongue protrusion more severely than posterior neocortex removal or dorsal frontal ablations. Complete frontal cortex lesions permit no sparing or recovery of tongue protrusion.

摘要

本文描述了一种测量大鼠舔舐时舌头伸出情况的技术。液体自动滴注到大鼠笼前的搁板上。一排间距为1毫米的16根光纤用作光探测器来测量舌头伸出情况。这些光纤激活与微型计算机相连的继电器，微型计算机对单个光束中断进行计数。该系统允许在对照大鼠和脑损伤大鼠的训练及测试过程中测量大量连续的舌头伸出情况。结果表明，腹侧额叶皮质损伤比去除后新皮质或背侧额叶切除更严重地破坏舌头伸出。完全的额叶皮质损伤则不会使舌头伸出得到保留或恢复。