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自体软骨在听骨链重建中的应用研究。

A Study of Use of Autologous Cartilage in Ossicular Reconstruction.

作者信息

Nagenahlli Siddappa Prakash, Poojar Jayakumar Puneeth, Jonnalagadda Dheeraj Kumar

机构信息

1Department of ENT, J.J.M Medical College, MCC B Block, Davangere, Karnataka 577004 India.

2Department of ENT, J.J.M Medical College, Davangere, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1431-1435. doi: 10.1007/s12070-018-1514-1. Epub 2018 Oct 19.

DOI:10.1007/s12070-018-1514-1
PMID:31750190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6841769/
Abstract

Ossiculoplasty is one of the commonly done and challenging surgery in otology and has been done using various graft materials. Materials such as autologous cartilage (tragal or conchal) or allograft (homograft) of the same tissue and synthetic materials like polyethylene TORP, ceramic and hydroxyapatite PORP or Titanium prosthesis have been used. But the latter synthetic materials are expensive and have high extrusion rates. Autologous cartilage grafts are selected for Ossiculoplasty as they are easy to harvest at the same site of operation, non-toxic, has less extrusion rate, minimum shrinkage and lateralization. The aim of this study is to know the efficacy of cartilage in ossicular reconstruction and to evaluate hearing outcome. It is a prospective study done on patients attending ENT outpatient department at hospitals attached to J.J.M Medical College, Davanagere. 50 patients were included in the study who underwent ossicular reconstruction either with canal wall up or down mastoidectomy with tympanoplasty. Pre-operative mean ABG was 39.3 db whereas 6 months post-operative mean ABG was 31.6 db with mean ABG improvement of 7.7 db which was statistically significant. Hearing improvement is better in cases where stapes suprastructure was present and also in canal wall up mastoidectomy procedures. This study suggests that cartilage graft (tragal and conchal) is effective in cases of ossicular reconstruction in patients of chronic otitis media and gives good hearing gain. It is also a economical option in developing countries.

摘要

听骨链成形术是耳科学中常见且具有挑战性的手术之一,已使用多种移植材料进行。已使用的材料包括自体软骨(耳屏或耳甲)或相同组织的同种异体移植(同种移植)以及合成材料,如聚乙烯全听骨赝复物、陶瓷和羟基磷灰石部分听骨赝复物或钛假体。但后几种合成材料价格昂贵且脱出率高。自体软骨移植被选用于听骨链成形术,因为它们易于在手术同一部位获取,无毒,脱出率低,收缩和移位最小。本研究的目的是了解软骨在听骨重建中的疗效并评估听力结果。这是一项对在达瓦纳盖雷J.J.M医学院附属医院耳鼻喉科门诊就诊的患者进行的前瞻性研究。50例接受了耳道上壁或下壁乳突根治术加鼓室成形术的听骨重建患者被纳入研究。术前平均气骨导差为39.3分贝,而术后6个月平均气骨导差为31.6分贝,平均气骨导差改善了7.7分贝,具有统计学意义。在镫骨上部结构存在的病例以及耳道上壁乳突根治术手术中听力改善更好。本研究表明,软骨移植(耳屏和耳甲)在慢性中耳炎患者听骨重建病例中有效,并能带来良好的听力增益。在发展中国家,这也是一种经济的选择。

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本文引用的文献

1
Hearing results after myringoplasty.鼓膜成形术后的听力结果。
Kathmandu Univ Med J (KUMJ). 2006 Oct-Dec;4(4):455-9.
2
Hearing results for ossicular reconstruction using a cartilage-connecting hydroxyapatite prosthesis with a spearhead.使用带矛头的软骨连接羟基磷灰石假体进行听骨重建的听力结果。
Otol Neurotol. 2007 Dec;28(8):1041-4. doi: 10.1097/MAO.0b013e31815aee37.
3
Type III cartilage "shield" tympanoplasty: an effective procedure for hearing improvement.III型软骨“盾牌”鼓膜成形术:一种改善听力的有效手术。
Otolaryngol Head Neck Surg. 2007 Jun;136(6):982-5. doi: 10.1016/j.otohns.2006.12.025.
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Hydroxyapatite versus titanium ossiculoplasty.羟基磷灰石与钛质听小骨成形术
Otol Neurotol. 2007 Jun;28(4):492-8. doi: 10.1097/01.mao.0000265203.92743.d1.
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Cartilage tympanoplasty.软骨鼓膜成形术
Otolaryngol Clin North Am. 2006 Dec;39(6):1161-76. doi: 10.1016/j.otc.2006.08.006.
6
Early results of titanium ossiculoplasty using the Kurz titanium prosthesis--a UK perspective.使用库尔兹钛质假体进行钛质听骨成形术的早期结果——英国视角
J Laryngol Otol. 2007 Jun;121(6):539-44. doi: 10.1017/S0022215106003999. Epub 2006 Nov 2.
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Otol Neurotol. 2002 Sep;23(5):643-6. doi: 10.1097/00129492-200209000-00006.
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Double cartilage block ossiculoplasty in chronic ear surgery.慢性耳部手术中的双软骨块听骨成形术
Laryngoscope. 1999 Jun;109(6):911-4. doi: 10.1097/00005537-199906000-00013.