Ortega E, Ruiz E, Osorio C
Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Granada, España.
Rev Esp Fisiol. 1988 Mar;44(1):13-6.
The effects of aging as well as body weight on conversion of circulating Androstendione (A) to Estrone (E1) in 21 postmenopausal women of different ages and body weights have been studied. Serum concentration of A and E1 were measured by RIA. The E1/A ratio was correlated with total body weight, body mass index, excessive body weight, age and years after cessation of menstruation. The results show that the E1/A ratio was significantly correlated with total body weight, body mass index and excessive body weight. In contrast the E1/A ratio is not significantly correlated with age or years after cessation of menstruation.
对21名不同年龄和体重的绝经后女性，研究了衰老以及体重对循环中的雄烯二酮（A）向雌酮（E1）转化的影响。采用放射免疫分析法测定血清中A和E1的浓度。E1/A比值与总体重、体重指数、超重、年龄及绝经年限相关。结果显示，E1/A比值与总体重、体重指数和超重显著相关。相比之下，E1/A比值与年龄或绝经年限无显著相关性。
