Carreras O, Bolufer J, Murillo M L
Departamento de Fisiología Animal, Facultad de Farmacia, Sevilla, Spain.
Rev Esp Fisiol. 1988 Mar;44(1):27-30.
Digestive enzymatic activities (maltase, lactase and sucrase) have been determined in the intestinal mucosa of rats subjected to a jejunoileal bypass of 45 cm. The weight and protein content of the mucosa (mg/cm) were significantly decreased in the bypassed segment and significantly increased in the unbypassed segment, as compared to control rats. Maltase, lactase and sucrase specific (U/g protein) and total activity (U/cm intestine) were significantly decreased in the bypassed jejunum, compared to sham-operated rats. In the ileum, maltase specific and total activities increased in bypassed animals while the lactase and sucrase activities remained unchanged.
已对接受45厘米空肠回肠旁路手术的大鼠肠黏膜中的消化酶活性（麦芽糖酶、乳糖酶和蔗糖酶）进行了测定。与对照大鼠相比，旁路肠段的黏膜重量和蛋白质含量（毫克/厘米）显著降低，未旁路肠段则显著增加。与假手术大鼠相比，旁路空肠中的麦芽糖酶、乳糖酶和蔗糖酶的比活性（单位/克蛋白质）和总活性（单位/厘米肠段）显著降低。在回肠中，旁路大鼠的麦芽糖酶比活性和总活性增加，而乳糖酶和蔗糖酶活性保持不变。
