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自体移植物、混合移植物和同种异体移植物在前交叉韧带重建中的临床结果及二次关节镜检查结果

Clinical outcomes and second-look arthroscopic findings of anterior cruciate ligament reconstruction with autograft, hybrid graft, and allograft.

作者信息

Zheng Xiaozuo, Hu Yang, Xie Peng, Li Tong, Feng Yu-E, Gu Juyuan, Gao Shijun

机构信息

Department of Orthopedics, Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, China.

Key Laboratory of Biomechanics of Hebei Province, No. 139 Ziqiang Road, Shijiazhuang, 050051, China.

出版信息

J Orthop Surg Res. 2019 Nov 21;14(1):380. doi: 10.1186/s13018-019-1439-8.

Abstract

BACKGROUND

There is no consensus as to the choice of grafts for primary anterior cruciate ligament (ACL) reconstruction. The purpose of this study was to compare the clinical and second-look arthroscopic outcomes after ACL reconstruction by use of autograft, hybrid graft, and γ-irradiated allograft.

METHODS

Ninety-seven patients who underwent second-look arthroscopy after ACL reconstruction with autografts (28 patients, hamstring autograft), hybrid grafts (32 patients, hamstring autograft augmented with γ-irradiated tibialis anterior tendon allograft), or γ-irradiated allografts (37 patients, tibialis anterior tendons) were included in this study. The clinical outcomes were compared by using Lysholm score, International Knee Documentation Committee (IKDC) score, and Tegner activity score, and the side-to-side differences of KT-1000 measurement. Second-look arthroscopic findings were compared in terms of synovial coverage and graft tension.

RESULTS

There were no statistical significances among the three groups in Lysholm score, IKDC score, or Tegner activity score (P > 0.05). The KT-1000 examination showed more anterior laxity in the γ-irradiated allograft group than in the autograft or hybrid graft groups (P = 0.006, and P = 0.013, respectively). Two patients in the autograft group, 2 patients in the hybrid graft group and 4 patients in the allograft group were evaluated as graft failure on second-look arthroscopy. The synovial coverage was superior in the autograft group than that in the hybrid graft group or the allograft group (P = 0.013 and P = 0.010, respectively), and was comparable between the hybrid graft group and allograft group (P = 0.876). With regard to graft tension, the autograft group and hybrid group were comparable (P = 0.883) but showed better results than the allograft group (P = 0.011 and P = 0.007, respectively).

CONCLUSION

The hamstring autografts and hybrid grafts used for ACL reconstruction produced equal efficacy but provided better knee stability than allografts. In addition, the hamstring autografts showed better synovial coverage than the other two graft types.

摘要

背景

对于初次前交叉韧带(ACL)重建移植物的选择尚无共识。本研究的目的是比较使用自体移植物、混合移植物和γ射线辐照同种异体移植物进行ACL重建后的临床和二次关节镜检查结果。

方法

本研究纳入了97例在ACL重建后接受二次关节镜检查的患者,其中自体移植物组(28例,腘绳肌自体移植物)28例,混合移植物组(32例,腘绳肌自体移植物联合γ射线辐照胫骨前肌腱同种异体移植物)32例,γ射线辐照同种异体移植物组(37例,胫骨前肌腱)37例。通过Lysholm评分、国际膝关节文献委员会(IKDC)评分和Tegner活动评分比较临床结果,并比较KT-1000测量的两侧差异。从滑膜覆盖和移植物张力方面比较二次关节镜检查结果。

结果

三组在Lysholm评分、IKDC评分或Tegner活动评分方面均无统计学意义(P>0.05)。KT-1000检查显示,γ射线辐照同种异体移植物组的前向松弛度高于自体移植物组或混合移植物组(分别为P = 0.006和P = 0.013)。自体移植物组有2例患者被评估为移植物失败,混合移植物组有2例,同种异体移植物组有4例。自体移植物组的滑膜覆盖优于混合移植物组或同种异体移植物组(分别为P = 0.013和P = 0.010),混合移植物组和同种异体移植物组之间相当(P = 0.876)。关于移植物张力,自体移植物组和混合组相当(P = 0.883)但均优于同种异体移植物组(分别为P = 0.011和P = 0.007)。

结论

用于ACL重建时,腘绳肌自体移植物和混合移植物疗效相当,但比同种异体移植物能提供更好的膝关节稳定性。此外,腘绳肌自体移植物的滑膜覆盖优于其他两种移植物类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e12b/6868796/d45d0140b5fa/13018_2019_1439_Fig1_HTML.jpg

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