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移植物选择以降低前交叉韧带重建的翻修率:一项全国性回顾性队列研究。

Graft choice to decrease the revision rate of anterior cruciate ligament reconstruction: a nationwide retrospective cohort study.

机构信息

Department of Orthopaedic Surgery, National Health Insurance Service Ilsan Hospital, 100 Ilsan-ro, Ilsandong-gu, Goyang, 10444, Republic of Korea.

Research Institute, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.

出版信息

Sci Rep. 2024 Aug 28;14(1):20004. doi: 10.1038/s41598-024-71068-0.

Abstract

There are many graft choices for anterior cruciate ligament (ACL) reconstruction, including autografts and allografts. The choice of graft has been identified as a significant factor affecting the outcome of ACL reconstruction. This study aimed to determine whether allograft or autograft is better for avoiding revisional ACL reconstruction. The National Health Insurance Service-Health screening database analyzed 146,122 patients who underwent ACL reconstruction surgery from Jan. 1, 2002, to Dec. 31, 2021. The study was conducted in two groups, autograft or allograft, and the rates of revision ACL reconstruction between the two groups were compared. Propensity score matching and multivariable Cox Proportional Hazard model analysis were used. The significant predictors for complications (p < 0.05) were as follows. The total of patients with ACL reconstruction was 146,122. Allograft was used in 121,148 patients, and autograft was used in 24,974 patients. 9.2% of the allograft group and 8.7% of the autograft group underwent revision ACL reconstruction. (P < .0001) 70.0% & 63.6% of patients underwent revision surgery within 1 year in the allograft & autograft groups, respectively. In summary, using autograft in primary ACL reconstruction is helpful in lowering the rate of revision surgery.

摘要

有许多移植物选择可用于前交叉韧带 (ACL) 重建,包括自体移植物和同种异体移植物。移植物的选择已被确定为影响 ACL 重建结果的重要因素。本研究旨在确定同种异体移植物或自体移植物在避免翻修 ACL 重建方面更好。国家健康保险服务-健康筛查数据库分析了 2002 年 1 月 1 日至 2021 年 12 月 31 日期间接受 ACL 重建手术的 146122 名患者。该研究分为自体移植物或同种异体移植物两组,比较两组之间翻修 ACL 重建的发生率。使用倾向评分匹配和多变量 Cox 比例风险模型分析。并发症的显著预测因素(p < 0.05)如下。共有 146122 名患者接受 ACL 重建。121148 名患者使用同种异体移植物,24974 名患者使用自体移植物。同种异体移植物组和自体移植物组中有 9.2%和 8.7%的患者进行了翻修 ACL 重建。(P < 0.0001)同种异体移植物组和自体移植物组分别有 70.0%和 63.6%的患者在 1 年内接受了翻修手术。总之,在初次 ACL 重建中使用自体移植物有助于降低翻修手术率。

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