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腹腔镜两阶段 Fowler-Stephens 或附睪固定术治疗睪丸结局的回顾性分析。

Retrospective analysis of testicular outcomes following laparoscopic two-stage Fowler Stephens orchidopexy.

机构信息

Department of Paediatric Surgery, Royal Hospital for Sick Children Edinburgh, Edinburgh, UK.

Department of Paediatric Surgery, Royal Hospital for Sick Children Edinburgh, Edinburgh, UK.

出版信息

J Pediatr Surg. 2020 Feb;55(2):300-303. doi: 10.1016/j.jpedsurg.2019.10.030. Epub 2019 Nov 5.

Abstract

AIM OF THE STUDY

Few large series report outcomes for laparoscopic two-stage Fowler Stephens orchidopexy (LFSO). The aims were to evaluate testicular outcomes and to identify factors predictive of successful outcome.

METHOD

A retrospective case series of children undergoing laparoscopic surgery for impalpable testes between May 1996 and March 2018 was reviewed. Data were collected from case and operative records. The primary outcomes of interest were testicular atrophy or re-ascent. Regression analysis was conducted to identify factors predictive of successful outcome. Data was expressed as median (IQR).

RESULTS

Of 279 patients (300 testes) undergoing laparoscopy for impalpable testis, 114 patients (128 testes) underwent LFSO. Eighty-five patients (96 testes) had adequate follow-up available (53 left; 43 right). Age at first stage was 19 (IQR 13-36) months. Fifteen children had relevant co-morbidities. Time between procedures was 7 (IQR 6-8) months. Longest follow-up available was 12.5 months (IQR 6.8-19.8). Atrophy occurred in 8 testes (8.3%), and ascent occurred in 6 (6.3%). No factors were significantly predictive of success, although a trend towards atrophy was seen amongst testes undergoing gubernacular division compared with a gubernaculum-sparing technique (p = 0.06; OR 3; 95% CI 0.97-9.3).

CONCLUSION

A successful outcome was seen amongst 82 of 96 testes (85%) undergoing LFSO, similar to previous reports. No factors were identified that significantly predicted outcome. Number of adverse outcomes was limited (hence possibility of type II error), and therefore preservation of the gubernaculum may reduce risk of testicular atrophy.

TYPE OF STUDY

Prognosis Study.

LEVEL OF EVIDENCE

Level IV.

摘要

研究目的

很少有大型系列研究报告腹腔镜两阶段 Fowler Stephens 或chidopexy(LFSO)的结果。目的是评估睾丸结局,并确定预测成功结果的因素。

研究方法

回顾性分析 1996 年 5 月至 2018 年 3 月期间接受腹腔镜手术治疗不可触及睾丸的儿童病例系列。数据来自病例和手术记录。主要观察指标为睾丸萎缩或再上升。回归分析用于确定预测成功结果的因素。数据表示为中位数(IQR)。

结果

在 279 例(300 个睾丸)接受腹腔镜不可触及睾丸手术的患者中,114 例(128 个睾丸)接受了 LFSO。85 例(96 个睾丸)有足够的随访资料(53 个左侧;43 个右侧)。第一阶段的年龄为 19 岁(IQR 13-36)个月。15 例儿童有相关合并症。两次手术之间的时间为 7 个月(IQR 6-8)。最长的随访时间为 12.5 个月(IQR 6.8-19.8)。发生萎缩 8 个睾丸(8.3%),上升 6 个睾丸(6.3%)。没有因素显著预测成功,但与保留精索技术相比,行精索分裂的睾丸有萎缩趋势(p=0.06;OR 3;95%CI 0.97-9.3)。

结论

在接受 LFSO 的 96 个睾丸中,有 82 个(85%)取得了成功的结果,与以往的报告相似。没有发现显著预测结果的因素。不良结果的数量有限(因此可能存在 II 类错误),因此保留精索可能会降低睾丸萎缩的风险。

研究类型

预后研究。

证据水平

IV 级。

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