School of Nursing, Hong Kong Polytechnic University, Hong Kong, China; Department of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China.
Guangzhou Municipal Centre for Disease and Control and Prevention, Guangzhou, China.
Ann Epidemiol. 2019 Dec;40:28-34.e2. doi: 10.1016/j.annepidem.2019.10.006. Epub 2019 Oct 31.
It is unclear whether migration would affect the mortality risk of breast cancer. In this study, we compared breast cancer mortality among three Chinese populations: Guangzhou (GZ)-born women, Hong Kong (HK)-born women, and HK residents who were born outside HK (HK immigrant), with the aim to explore the impact of migrant status on breast cancer mortality.
We applied an age-period-cohort model to annual age-specific mortality rates of breast cancer among GZ-born, HK-born, and HK-immigrant women from 2003 to 2016, respectively. We also projected mortality rates from 2017 to 2030.
Annual age-standardized mortality rate of breast cancer in women aged 35 years or older was 9.18, 9.17, and 9.83 per 100,000 population, for GZ-born, HK-born, and HK-immigrant women, respectively. A decreasing trend was found in the post-1950s cohorts of GZ-born women and in the post-1960s cohorts of two HK populations. Annual mortality rates of breast cancer in these populations were projected to decrease among the 35-64 years age group and increase among the 65 years and older age group in 2017-2030.
We found higher age-specific mortality rates of breast cancer in HK-immigrant women compared with HK- and GZ-born women, suggesting that immigration status might have an impact on breast cancer mortality.
目前尚不清楚迁移是否会影响乳腺癌的死亡风险。在这项研究中，我们比较了三个中国人群的乳腺癌死亡率：广州（GZ）出生的女性、香港（HK）出生的女性和在港出生的香港居民（香港移民），旨在探讨移民身份对乳腺癌死亡率的影响。
我们分别应用年龄-时期-队列模型来分析 2003 年至 2016 年期间 GZ 出生、HK 出生和 HK 移民女性的乳腺癌年龄特异性死亡率，并预测 2017 年至 2030 年的死亡率。
年龄标准化的 35 岁及以上女性乳腺癌年死亡率分别为 GZ 出生、HK 出生和 HK 移民女性的 9.18、9.17 和 9.83/100,000 人。在 GZ 出生女性的 1950 年后出生队列和两个香港人群的 1960 年后出生队列中，均发现呈下降趋势。这些人群中 35-64 岁年龄组的乳腺癌年死亡率预计在 2017-2030 年期间下降，65 岁及以上年龄组的死亡率则上升。
我们发现，与 HK 出生和 GZ 出生的女性相比，HK 移民女性的乳腺癌特定年龄死亡率更高，表明移民身份可能对乳腺癌死亡率有影响。
