Mahomed Nasreen, Reubenson Gary
Department of Radiology, Faculty of Health Sciences, University of the Witwatersrand, South Africa.
Department of Paediatrics & Child Health, Faculty of Health Sciences, University of the Witwatersrand, South Africa.
SA J Radiol. 2017 Nov 14;21(2):1257. doi: 10.4102/sajr.v21i2.1257. eCollection 2017.
Immune Reconstitution Inflammatory Syndrome (IRIS) refers to a collection of inflammatory disorders, predominantly related to infectious processes that manifest after the initiation of antiretroviral therapy (ART) and can be classified as unmasking or paradoxical. The prevalence of IRIS in children in sub-Saharan Africa is low. Approximately half of all cases are associated with . It may be difficult to distinguish IRIS from tuberculosis and other opportunistic infections radiologically; therefore, radiological findings must be interpreted with clinical and laboratory findings. In this review article, we describe the clinical and radiological manifestations of IRIS in children and provide illustrative radiological examples.
免疫重建炎症综合征（IRIS）指的是一组炎症性疾病，主要与抗逆转录病毒治疗（ART）开始后出现的感染过程相关，可分为暴露型或矛盾型。撒哈拉以南非洲儿童中IRIS的患病率较低。所有病例中约有一半与……有关。从放射学角度很难将IRIS与结核病和其他机会性感染区分开来；因此，必须结合临床和实验室检查结果来解读放射学检查结果。在这篇综述文章中，我们描述了儿童IRIS的临床和放射学表现，并提供了具有说明性的放射学实例。
