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抽脂术治疗下肢淋巴水肿:一项全面的系统评价

Lipoaspiration for the Treatment of Lower Limb Lymphedema: A Comprehensive Systematic Review.

作者信息

Forte Antonio J, Huayllani Maria T, Boczar Daniel, Ciudad Pedro, McLaughlin Sarah A

机构信息

Plastic Surgery, Mayo Clinic Florida - Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Jacksonville, USA.

Plastic, Reconstructive and Burn Surgery, Arzobispo Loayza National Hospital, Lima, PER.

出版信息

Cureus. 2019 Oct 15;11(10):e5913. doi: 10.7759/cureus.5913.

DOI:10.7759/cureus.5913
PMID:31754590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6827692/
Abstract

Lipoaspiration is a potential treatment for lymphedema; however, there is a lack of knowledge regarding the outcomes and benefits of this procedure in lower limb lymphedema. We aim to describe the outcomes of studies to date reporting the use of lipoaspiration in lower limb lymphedema. We searched the PubMed database for studies that evaluated the use of lipoaspiration for lower limb lymphedema. The keywords "lipoaspiration" AND "lymphedema," synonyms, and different combinations were used for the search. Only English studies were included. Eight studies met the inclusion criteria from a total of 129 articles. A volume reduction greater than 50% was found in all patients who underwent lipoaspiration for lower limb lymphedema. Complete volume reduction was found after four to five years of follow-up. A greater volume reduction was found for secondary lymphedema when compared to primary lymphedema. Finally, improvement was found in functionality, quality of life, and rate of infection. Lipoaspiration is recommended for patients with lower limb lymphedema in stages 2 and 3 of the disease, followed by controlled compressive therapy that maintains the volume reduction accomplished by the procedure.

摘要

脂肪抽吸术是治疗淋巴水肿的一种潜在方法;然而,对于该手术在下肢淋巴水肿中的疗效和益处,人们了解不足。我们旨在描述迄今为止报告脂肪抽吸术用于下肢淋巴水肿的研究结果。我们在PubMed数据库中搜索了评估脂肪抽吸术用于下肢淋巴水肿的研究。搜索使用了关键词“脂肪抽吸术”和“淋巴水肿”、同义词以及不同的组合。仅纳入英文研究。在总共129篇文章中,有8项研究符合纳入标准。所有接受下肢淋巴水肿脂肪抽吸术的患者均出现了超过50%的体积减小。随访四到五年后发现体积完全减小。与原发性淋巴水肿相比,继发性淋巴水肿的体积减小更为明显。最后,在功能、生活质量和感染率方面均有改善。对于处于疾病2期和3期的下肢淋巴水肿患者,建议采用脂肪抽吸术,随后进行控制性压迫治疗,以维持手术所实现的体积减小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f4/6827692/621ee4e75738/cureus-0011-00000005913-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f4/6827692/621ee4e75738/cureus-0011-00000005913-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78f4/6827692/621ee4e75738/cureus-0011-00000005913-i01.jpg

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