Expert Centre of Lympho-Vascular Medicine, Departments of Vascular Surgery, Nij Smellinghe Hospital, Drachten, The Netherlands.
Departments of Dermatology, Nij Smellinghe Hospital, Drachten, The Netherlands.
Br J Surg. 2017 Jan;104(1):84-89. doi: 10.1002/bjs.10325. Epub 2016 Nov 3.
The treatment of end-stage lymphoedema of the leg is challenging, especially when conservative treatment fails and there is a large volume difference between the affected and unaffected legs. Circumferential suction-assisted lipectomy (CSAL) has been described as a treatment option for end-stage lymphoedema of the leg. Here, the long-term results of CSAL in end-stage primary and secondary lymphoedema of the leg were analysed.
This was a descriptive study of patients treated with CSAL for unilateral chronic irreversible lymphoedema of the leg. Compression therapy was resumed after surgery. Leg volumes were measured before surgery, and at 1, 6, 12 and 24 months after the procedure.
A total of 47 patients with primary lymphoedema had a median preoperative volume difference between affected and unaffected legs of 3686 (i.q.r. 2851-5121) ml. Two years after surgery, this volume difference was reduced to 761 ml, a 79 per cent reduction. In the 41 patients treated for secondary lymphoedema, the median preoperative volume difference was 3320 (i.q.r. 2533-4783) ml, decreasing after 2 years to -38 ml (101 per cent reduction). The preoperative volume difference and the sex of the patient significantly influenced the final outcome after 2 years. The outcome was not related to BMI or other patient characteristics.
CSAL is an effective method for treating both primary and secondary lymphoedema of the leg.
腿部终末期淋巴水肿的治疗具有挑战性,尤其是在保守治疗失败且患侧和健侧之间存在较大体积差异的情况下。环周抽吸辅助脂肪切除术(CSAL)已被描述为腿部终末期淋巴水肿的一种治疗选择。在此,分析了 CSAL 治疗腿部原发性和继发性终末期淋巴水肿的长期结果。
这是一项针对接受 CSAL 治疗单侧慢性不可逆腿部淋巴水肿的患者的描述性研究。手术后恢复了压缩治疗。在手术前、手术后 1、6、12 和 24 个月测量腿部体积。
47 例原发性淋巴水肿患者的患侧和健侧术前体积差异中位数为 3686(IQR 2851-5121)ml。手术后 2 年,体积差异缩小至 761 ml,减少了 79%。41 例继发性淋巴水肿患者的术前体积差异中位数为 3320(IQR 2533-4783)ml,2 年后减少至-38 ml(减少 101%)。术前体积差异和患者性别对 2 年后的最终结果有显著影响。结果与 BMI 或其他患者特征无关。
CSAL 是治疗腿部原发性和继发性淋巴水肿的有效方法。