Hormati Ahmad, Aminnejad Reza, Saeidi Mohammad, Ghadir Mohammad Reza, Mohammadbeigi Abolfazl, Shafiee Hamed
Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran.
Gastrointestinal and Liver Disease Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Anesth Pain Med. 2019 Aug 26;9(4):e95796. doi: 10.5812/aapm.95796. eCollection 2019 Aug.
Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic method for treatment of many biliary diseases. With respect to rapid recovery and more patient comfort, this procedure is currently performed under light general anesthesia (GA) or conscious sedation.
The current study aimed to clarify that intravenous sedation or light general anesthesia can be performed without great fear of anesthesia related complications in ERCP patients and sedative doses of propofol can be used safely in outpatient settings under the supervision of an expert anesthesiologist.
This is a cross-sectional study on 1023 ERCP patients under light GA during 2014 - 2018 in Qom, Shahid Beheshti Hospital. Data were collected by a checklist and were analyzed by using chi-square test in SPSS V.22.
From 1023 patients, 501 (48.97 %) were male and 522 (51.03 %) were female with a mean age of 47.2 ± 6.7 years. The most common finding in ERCP was choledocholithiasis (76.15 %). The most common complication was hemodynamic instability (37.01 %) followed by desaturation (11.65 %) both of them ware anesthesia related. Prevalence of GI (gastrointestinal) related complications was 13.39 %. The most common GI related complications were pancreatitis (7.92 %) and bleeding (3.32 %). Total mortality rate was 0.88 %.
ERCP-related complications are inevitable but can be controlled by early diagnosis and clinical experience. Severe complications and high risk patients may increase the mortality and morbidity of the procedure. Anesthesia related complications are more frequent than GI related unwanted events. Fortunately, the most common anesthesia related complications are readily manageable and are minor in nature when an expert anesthesiologist is present in the scene. Close monitoring of the patient's vital signs should be the mainstay of the safe procedure.
内镜逆行胰胆管造影术(ERCP)是一种用于治疗多种胆道疾病的内镜方法。鉴于其恢复快且患者舒适度更高,目前该手术在浅全身麻醉(GA)或清醒镇静下进行。
本研究旨在阐明,在ERCP患者中,静脉镇静或浅全身麻醉可以在无需过度担心麻醉相关并发症的情况下实施,并且丙泊酚的镇静剂量可以在专家麻醉医师的监督下在门诊环境中安全使用。
这是一项对2014年至2018年期间在库姆市沙希德·贝赫什提医院接受浅全身麻醉的1023例ERCP患者进行的横断面研究。数据通过检查表收集,并在SPSS V.22中使用卡方检验进行分析。
1023例患者中,501例(48.97%)为男性,522例(51.03%)为女性,平均年龄为47.2±6.7岁。ERCP中最常见的发现是胆总管结石(76.15%)。最常见的并发症是血流动力学不稳定(37.01%),其次是血氧饱和度下降(11.65%),这两者均与麻醉相关。胃肠道(GI)相关并发症的发生率为13.39%。最常见的GI相关并发症是胰腺炎(7.92%)和出血(3.32%)。总死亡率为0.88%。
ERCP相关并发症不可避免,但可通过早期诊断和临床经验加以控制。严重并发症和高危患者可能会增加手术的死亡率和发病率。麻醉相关并发症比GI相关不良事件更频繁。幸运的是,当有专家麻醉医师在场时,最常见的麻醉相关并发症易于处理且性质轻微。密切监测患者的生命体征应是安全手术的主要手段。