Suppr超能文献

激光前列腺切除术中光纤运动对组织消融的依赖性。

Dependence of laser-induced tissue ablation on optical fiber movements for laser prostatectomy.

机构信息

Department of Biomedical Engineering and Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University, Busan, 48513, Republic of Korea.

Department of Urology, Weill Cornell Medicine, New York, NY, USA.

出版信息

World J Urol. 2020 Sep;38(9):2253-2259. doi: 10.1007/s00345-019-03019-8. Epub 2019 Nov 21.

Abstract

PURPOSE

The aim of the current study was to identify the efficient fiber movements for 532-nm laser prostatectomy.

MATERIALS AND METHODS

532-nm Lithium triborate (LBO) laser light was tested on 120 kidney tissues at three different translational speeds (TS 1, 2, and 4 mm/s) and four different rotational speeds (RS 0.5, 1.0, 1.6, and 2.1 rad/s). The applied power was 120 W at a 2-mm working distance and 60° sweeping angle. Ablation rate and dimensions of resulting ablation craters were measured.

RESULTS

Slower TSs and RSs created deeper and wider ablation craters with thinner coagulation, leading to more efficient ablation performance. Maximal ablation rate was achieved at a TS of 2 mm/s and RSs of 0.5 and 1.0 rad/s. An RS of 0.5 rad/s accompanied surface carbonization for all the TSs. Irrespective of TS, ablation rate became saturated at faster RSs than 1.0 rad/s. Faster TSs or RSs reduced tissue ablation, but increased thermal coagulation due to a shorter interaction time.

CONCLUSIONS

Optimal ablation efficiency occurred at a TS of 2 mm/s and a RS of 1.0 rad/s with a thin coagulation of around 1.0 mm and no or minimal carbonization. Further studies will validate the current findings with prostate tissue and high-power levels for laser prostatectomy.

摘要

目的

本研究旨在确定 532nm 激光前列腺切除术的有效光纤运动。

材料与方法

在三种不同的平移速度(TS1、2 和 4mm/s)和四种不同的旋转速度(RS0.5、1.0、1.6 和 2.1rad/s)下,对 120 个肾脏组织进行了 532nm 硼酸锂(LBO)激光测试。应用功率为 120W,工作距离为 2mm,扫掠角为 60°。测量了消融速率和产生的消融坑的尺寸。

结果

较慢的 TS 和 RS 产生了更深、更宽的消融坑,且凝固层较薄,导致消融效果更好。在 TS 为 2mm/s 和 RS 为 0.5 和 1.0rad/s 时,达到了最大的消融速率。RS 为 0.5rad/s 时,所有 TS 都伴有表面碳化。无论 TS 如何,在比 1.0rad/s 更快的 RS 下,消融速率都会达到饱和。更快的 TS 或 RS 会减少组织消融,但由于相互作用时间较短,会增加热凝固。

结论

在 TS 为 2mm/s 和 RS 为 1.0rad/s、凝固层约为 1.0mm、无碳化或碳化最小的情况下,可实现最佳消融效率。进一步的研究将用前列腺组织和高功率水平验证当前的发现。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验