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[儿童绿茶中毒导致的重症肝炎。病例报告]

[Severe hepatitis caused by green tea intoxication in a child. Case report].

作者信息

D'Agostino Daniel, Cavalieri María L, Arcucci María S

机构信息

Servicio de Gastroenterología, Hepatología y Trasplante Hepático e Intestinal Pediátrico del Hospital Italiano de Buenos Aires, Argentina.

出版信息

Arch Argent Pediatr. 2019 Dec 1;117(6):e655-e658. doi: 10.5546/aap.2019.e655.

Abstract

Herb-induced liver injury is a type of adverse drug reaction related to using herbal medicine, and now is a segment of druginduced liver injury. The use of herbal products has increased significantly, because it is generally regarded as safe and natural by the public. In the United States, the incidence reaches 9 % and, in the countries of Asia, 19-63 % of the total cases of druginduced liver injury. Green tea is obtained from the leaves of the Camellia sinensis. Freshly harvested leaves are stabilized by dry heating to inactivate the polyphenol enzyme and then dried quickly. Its consumption has increased in recent years and has been reported with hepatotoxic reactions. We present a case of severe hepatitis related to the consumption of green tea in a 2-year-old child.

摘要

草药性肝损伤是一种与使用草药相关的药物不良反应,现在是药物性肝损伤的一部分。草药产品的使用显著增加,因为它通常被公众视为安全且天然的。在美国,其发病率达到9%,在亚洲国家,占药物性肝损伤总病例的19% - 63%。绿茶由茶树的叶子制成。新鲜采摘的叶子通过干热进行稳定处理,以灭活多酚酶,然后迅速干燥。近年来其消费量有所增加,并且有肝毒性反应的报道。我们报告一例2岁儿童因饮用绿茶导致严重肝炎的病例。

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