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[绿茶引发的中毒性肝炎]

[Toxic hepatitis triggered by green tea].

作者信息

Rohde Johan, Jacobsen Claire, Kromann-Andersen Hans

机构信息

Medicinsk Afdeling, Glostrup Hospital, Denmark.

出版信息

Ugeskr Laeger. 2011 Jan 17;173(3):205-6.

Abstract

Green tea is associated with various beneficial health effects, but several cases of hepatotoxic side effects have been reported. We present the first Danish case of toxic hepatitis following the consumption of 4-6 cups of green tea per day for six months. Green tea's main chemical component is epigallocatechin gallate (EGCG). Animal studies have shown that EGCG accumulated in the liver is most toxic when consumed fasting and that it causes greater hepatotoxicity upon repeated administration. Green tea hepatotoxicity should be kept in mind and cases are notifiable to the food authorities.

摘要

绿茶具有多种有益健康的功效,但也有几例肝毒性副作用的报道。我们报告丹麦首例因连续六个月每天饮用4 - 6杯绿茶而导致中毒性肝炎的病例。绿茶的主要化学成分是表没食子儿茶素没食子酸酯(EGCG)。动物研究表明,空腹饮用时,肝脏中积累的EGCG毒性最大,且重复给药时会导致更大的肝毒性。应牢记绿茶的肝毒性,此类病例需向食品管理部门报告。

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