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MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease.

作者信息

Zhao W, Wang P, He W, Tao T, Li H, Li Y, Jiang W, Sun J, Ge X, Chen X, Zheng Y, Wei L, Chen C, Wang Y, Li C, Chen H, Yao B, Tang W, Zhu M

机构信息

State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China; Reproductive Medical Center, Jinling Hospital Affiliated Medical School of Nanjing University, Nanjing, China.

State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Ministry of Education (MOE) Key Laboratory of Model Animal for Disease Study and the Medical School of Nanjing University, Nanjing, China.

出版信息

Cell Mol Gastroenterol Hepatol. 2020;9(2):345-347.e6. doi: 10.1016/j.jcmgh.2019.11.003. Epub 2019 Nov 20.

DOI:10.1016/j.jcmgh.2019.11.003
PMID:31759145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6997446/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/35a609f5be5f/fx4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/619ebecf2d72/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/ae90fa552ffe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/4cb7304c838b/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/b90a82e249bb/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/e3cfe60da450/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/35a609f5be5f/fx4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/619ebecf2d72/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/ae90fa552ffe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/4cb7304c838b/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/b90a82e249bb/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/e3cfe60da450/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5b7/6997446/35a609f5be5f/fx4.jpg

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J Neurogastroenterol Motil. 2016 Apr 30;22(2):213-25. doi: 10.5056/jnm15186.
2
Laparoscopic assistance for primary transanal pull-through in Hirschsprung's disease: a systematic review and meta-analysis.腹腔镜辅助在先天性巨结肠症一期经肛门拖出术中的应用：一项系统评价和荟萃分析。
BMJ Open. 2015 Mar 24;5(3):e006063. doi: 10.1136/bmjopen-2014-006063.
3
Open versus transanal pull-through for Hirschsprung disease: a systematic review of long-term outcome.
先天性巨结肠症的开放手术与经肛门拖出术：长期疗效的系统评价
Eur J Pediatr Surg. 2013 Apr;23(2):94-102. doi: 10.1055/s-0033-1343085. Epub 2013 Apr 9.
4
Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1.肌球蛋白磷酸酶靶蛋白 1 缺失小鼠的肠道平滑肌收缩表型改变。
Gastroenterology. 2013 Jun;144(7):1456-65, 1465.e1-5. doi: 10.1053/j.gastro.2013.02.045. Epub 2013 Mar 13.
5
Methionine enhances the contractile activity of human colon circular smooth muscle in vitro.蛋氨酸增强人结肠环形平滑肌的体外收缩活性。
J Korean Med Sci. 2012 Jul;27(7):777-83. doi: 10.3346/jkms.2012.27.7.777. Epub 2012 Jun 29.
6
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