Davidson R N, Lynn W, Savage P, Wansbrough-Jones M H
Department of Communicable Diseases and Radiology, St George's Hospital, London.
Thorax. 1988 Aug;43(8):627-30. doi: 10.1136/thx.43.8.627.
Of 13 patients with chickenpox pneumonia (12 of them adults) treated during 1979-87, 10 received antiviral drugs--nine acyclovir and one vidarabine. Three died despite intensive treatment. Serious secondary infections occurred in six cases. There were no clear indications that antiviral treatment altered the natural history of the condition. Acyclovir may at present be used too late in the course of chickenpox pneumonia to alter its outcome.
在1979年至1987年期间接受治疗的13例水痘肺炎患者中(其中12例为成年人),10例接受了抗病毒药物治疗,9例使用阿昔洛韦,1例使用阿糖腺苷。尽管进行了强化治疗,仍有3例死亡。6例发生了严重的继发感染。没有明确迹象表明抗病毒治疗改变了病情的自然病程。目前,阿昔洛韦在水痘肺炎病程中使用可能为时已晚,无法改变其结局。