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老年人的慢性疾病和抑郁症状:功能限制的中介作用。

Chronic conditions and depressive symptoms in older adults: the mediating role of functional limitations.

机构信息

College of Nursing, Pennsylvania State University, University Park, PA, USA.

出版信息

Aging Ment Health. 2021 Feb;25(2):243-249. doi: 10.1080/13607863.2019.1693971. Epub 2019 Nov 25.

Abstract

BACKGROUND

Depressive symptoms, chronic conditions, and functional limitations are common in older adults. Several studies have examined the relationship between chronic conditions or functional limitations and depressive symptoms separately. However, little is known about how much of the effect of chronic conditions on depressive symptoms is due to the functional limitations resulting from such conditions.

METHODS

This paper examined the longitudinal association of chronic conditions and functional limitations with depressive symptoms in older adults aged 65 and over in the USA using the data from the 2012 wave and 2014 wave of the Health and Retirement Study (HRS). Mediation analysis was used to examine the mediation effects of 2012 functional limitations on the relationship between 2012 chronic conditions and 2014 depressive symptoms controlling for other measures including gender, age, race, education, marital status, and BMI.

RESULTS

Results revealed that chronic conditions and functional limitations were significantly associated with depressive symptoms. There was a 13.7% mediation effect when 2012 functional limitations were added as a mediator on the relationship between 2012 chronic conditions and 2014 depressive symptoms.

CONCLUSION

Functional limitations mediate the relationship between chronic conditions and depressive symptoms. Preventing or managing functional limitations may help reduce depressive symptoms in older adults with chronic conditions.

摘要

背景

抑郁症状、慢性疾病和功能限制在老年人中很常见。有几项研究分别检查了慢性疾病或功能限制与抑郁症状之间的关系。然而,对于慢性疾病对抑郁症状的影响有多少是由于这些疾病导致的功能限制,人们知之甚少。

方法

本研究使用美国健康与退休研究(HRS)2012 年和 2014 年的数据,考察了 65 岁及以上老年人的慢性疾病和功能限制与抑郁症状之间的纵向关联。中介分析用于检验 2012 年功能限制在 2012 年慢性疾病与 2014 年抑郁症状之间关系中的中介效应,控制了性别、年龄、种族、教育、婚姻状况和 BMI 等其他措施。

结果

结果显示,慢性疾病和功能限制与抑郁症状显著相关。当将 2012 年功能限制作为中介变量加入到 2012 年慢性疾病与 2014 年抑郁症状之间的关系中时,存在 13.7%的中介效应。

结论

功能限制在慢性疾病和抑郁症状之间起中介作用。预防或管理功能限制可能有助于减少患有慢性疾病的老年人的抑郁症状。

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