Alfazaz Askia, Assoumane Ibrahim, Adakal Ousseini, Adamou Harissou, Magagi Ibrahim Amadou, Baaré Ibrahim
ENT Department, CHR of Maradi, Maradi, Niger Republic.
Neurosurgery Department, Reference Hospital Maradi, Maradi, Niger Republic.
Pan Afr Med J. 2019 Sep 25;34:51. doi: 10.11604/pamj.2019.34.51.20255. eCollection 2019.
Rhabdomyosarcoma (RMS), a tumor of skeletal muscle origin, is the most common soft tissue sarcoma encountered in childhood and adolescence; it is primarily found in the head and neck region, it is relatively uncommon tumors of the oral cavity. Clinical signs depend on the exact location of the lesion in the oral cavity and its development. Authors reported the case of a 14-year-old patient who presented an oropharyngeal mass causing voice dysfunction, after two surgical operation the patient experimented two 2 recurrences of the lesion. The histopathological examination objectifies an oropharyngeal rhabdomyosarcoma. Immediate postoperative outcome was uneventful with improvement in the voice dysfunction and dysphagia one month after surgery. Complementary treatment (chemotherapy and radiotherapy) was not available and accessible to the patient. Twenty months (20) after surgery, the examination found a recurrence of the tumor with pulmonary metastases and neurological complications. Oropharyngeal rhabdomyosarcomas are rare. Their interest lies in the fact that they often affect children and adolescents. The prognosis remains unfavorable in our context, even for cases accessible to surgery since complementary treatment with chemotherapy and / or radiotherapy does not exist. The prognosis depends on tumor size, location, staging, age of patients and especially the quality of the management.
横纹肌肉瘤(RMS)是一种起源于骨骼肌的肿瘤,是儿童和青少年时期最常见的软组织肉瘤;它主要发生在头颈部区域,在口腔中相对少见。临床症状取决于病变在口腔中的具体位置及其发展情况。作者报告了一例14岁患者的病例,该患者出现口咽肿物并导致声音功能障碍,经过两次手术,患者经历了两次病变复发。组织病理学检查确诊为口咽横纹肌肉瘤。术后即刻结果平稳,术后一个月声音功能障碍和吞咽困难有所改善。患者无法获得辅助治疗(化疗和放疗)。术后20个月,检查发现肿瘤复发并伴有肺转移和神经并发症。口咽横纹肌肉瘤很罕见。它们的关注点在于常常影响儿童和青少年。在我们的情况下,预后仍然不佳,即使对于可进行手术的病例也是如此,因为不存在化疗和/或放疗的辅助治疗。预后取决于肿瘤大小、位置、分期、患者年龄,尤其是治疗质量。