Tandon Ankita, Sethi Kanika, Pratap Singh Anand
Assistant Professor, Department of Oral Pathology & Microbiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India.
Senior Lecturer, Department of Oral Pathology & Microbiology, Indraprastha Dental, College & Hospital, New Delhi, India.
J Clin Exp Dent. 2012 Dec 1;4(5):e302-8. doi: 10.4317/jced.50926.
Rhabdomyosarcoma (RMS) is a rare malignant soft tissue neoplasm comprised of cells derived from the primitive mesen¬chyme. About 35% of RMS arises in the head and neck, are are classified as parameningeal and non-parameningeal forms. These are the most common soft tissue sarcoma of the children, adolescents and young adults. Their etiopathogenesis and its molecular relevance have been emphasized. The first line of treatment is radical excision and this is usually supplemented by radiotherapy. It is believed that adjunct combination chemotherapy may greatly improve the prognosis. Inadequately treated tumours grow in an infiltrative manner and recur in a high percentage of cases. Bone does not constitute an effective barrier to the growth of the tumour and bone invasion is a frequent finding in head and neck rhabdomyosarcomas. Key words:Rhabdomyosarcomas, botryoid, spindle, alveolar, sarcomas, undifferentiated.
横纹肌肉瘤（RMS）是一种罕见的恶性软组织肿瘤，由原始间充质来源的细胞组成。约35%的RMS发生于头颈部，分为脑膜旁和非脑膜旁型。这些是儿童、青少年和年轻成人中最常见的软组织肉瘤。其病因发病机制及其分子相关性已受到关注。一线治疗是根治性切除，通常辅以放疗。据信辅助联合化疗可大大改善预后。治疗不充分的肿瘤呈浸润性生长，复发率很高。骨并非肿瘤生长的有效屏障，骨侵犯在头颈部横纹肌肉瘤中很常见。关键词：横纹肌肉瘤、葡萄状、梭形、肺泡状、肉瘤、未分化型
