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内镜下黏膜下切除术与内镜下黏膜下透热疗法治疗下鼻甲肥大的比较

Endoscopic Submucosal Resection Versus Endoscopic Submucosal Diathermy for Inferior Turbinate Hypertrophy.

作者信息

Lukka Vijay Kumar, Kurien Regi, Varghese Lalee, Rupa Vedantam

机构信息

Department of Otorhinolaryngology, Christian Medical College, Vellore, 632004 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1885-1894. doi: 10.1007/s12070-018-1280-0. Epub 2018 Feb 20.

Abstract

Endoscopic submucous resection and endoscopic submucous diathermy of the inferior turbinate are two different surgical methods of reducing size in turbinate hypertrophy. We aimed to compare the efficacy of both methods in reducing the nasal symptoms and improving nasal airway. This is a prospective randomized controlled trial conducted in a tertiary hospital, involving fifty patients with inferior turbinate hypertrophy not relieved by medications. After preoperative airway grading using a subjective symptom score, objective airway score and endoscopic score, patients were randomized to undergo either endoscopic submucous diathermy or endoscopic submucous resection. The primary outcome was postoperative improvement of airway and reduction of nasal symptoms. Secondary outcomes were postoperative bleeding and pain. All 24 patients who underwent endoscopic submucous diathermy and 26 who underwent endoscopic submucous resection showed statistically significant reduction in nasal symptoms both in the immediate and late postoperative periods. Patients who underwent endoscopic submucous resection showed greater improvement of airway at 1 week than those who had endoscopic submucous diathermy ( = 0.001). This difference however equalized at the 3-6 months postoperative period. Postoperative bleeding ( = 0.02) and pain ( = 0.04) were significantly more in patients who underwent endoscopic submucous resection. Both endoscopic submucous diathermy and endoscopic submucous resection are equally effective in improving airway in inferior turbinate hypertrophy with a slight advantage of endoscopic submucous resection in the early postoperative period. Reduced postoperative bleeding and pain may make endoscopic submucous diathermy a more attractive option overall.

摘要

下鼻甲内镜下黏膜下切除术和内镜下黏膜下透热疗法是两种不同的鼻甲肥大缩小手术方法。我们旨在比较这两种方法在减轻鼻部症状和改善鼻气道方面的疗效。这是一项在三级医院进行的前瞻性随机对照试验,纳入了50例药物治疗无效的下鼻甲肥大患者。在使用主观症状评分、客观气道评分和内镜评分进行术前气道分级后,患者被随机分为接受内镜下黏膜下透热疗法或内镜下黏膜下切除术。主要结局是术后气道改善和鼻部症状减轻。次要结局是术后出血和疼痛。所有接受内镜下黏膜下透热疗法的24例患者和接受内镜下黏膜下切除术的26例患者在术后即刻和晚期鼻部症状均有统计学意义的减轻。接受内镜下黏膜下切除术的患者在术后1周时气道改善程度大于接受内镜下黏膜下透热疗法的患者(P = 0.001)。然而,这种差异在术后3至6个月时趋于平衡。接受内镜下黏膜下切除术的患者术后出血(P = 0.02)和疼痛(P = 0.04)明显更多。内镜下黏膜下透热疗法和内镜下黏膜下切除术在改善下鼻甲肥大气道方面同样有效,内镜下黏膜下切除术在术后早期略有优势。术后出血和疼痛的减少可能使内镜下黏膜下透热疗法总体上成为更具吸引力的选择。

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