Filella X, Molina R, Piqué J M, Grau J J, Garcia-Valdecasas J C, Biete A, Novell F, Astudillo E, Bordas J M, Campo E
Department of Clinical Biochemistry (Unit of Cancer Research), Hospital Clinic i Provincial, Barcelona, Spain.
Anticancer Res. 1994 Mar-Apr;14(2B):705-8.
We have measured serum CEA levels in 207 patients with colorectal cancer. CEA sensitivity was related to tumor stage in tumors located in the right colon, but not in tumors located in the left colon or the rectum. CEA had prognostic value in patients with tumors located in the right colon (p < 0.001) but not in the left colon or the rectum. However, CEA did not have prognostic value independent of Dukes stage even in tumors in the right colon. Our results underline the different sensitivities and prognostic values for primary tumors in the left and right colorectal regions.
我们检测了207例结直肠癌患者的血清癌胚抗原（CEA）水平。在位于右半结肠的肿瘤中，CEA敏感性与肿瘤分期相关，但在位于左半结肠或直肠的肿瘤中并非如此。CEA对右半结肠肿瘤患者具有预后价值（p<0.001），但对左半结肠或直肠肿瘤患者则没有。然而，即使在右半结肠肿瘤中，CEA也没有独立于Dukes分期的预后价值。我们的结果强调了结直肠左右区域原发性肿瘤的不同敏感性和预后价值。
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