Shenzhen Key Laboratory of Affective and Social Cognitive Science, Shenzhen University, Shenzhen, China; School of Psychology, Shenzhen University, Shenzhen, China.
Department of Psychology, Zhejiang Normal University, Jinhua, China.
Horm Behav. 2020 Feb;118:104634. doi: 10.1016/j.yhbeh.2019.104634. Epub 2019 Nov 27.
Circulating levels of testosterone have been positively associated with impulsivity. The present study investigates the effect of testosterone administration on impulsivity in an intertemporal choice task, where participants are given a choice between smaller-sooner rewards and larger-later rewards. Healthy young male participants (n = 111) received a single-dose of 150 mg testosterone gel in a double-blind, placebo-controlled, between-subjects design. At 180 min post-administration, participants performed the decision-making task. Both model-free (i.e., higher indifference point) and model-based (i.e., steeper discounting rate) parameters revealed that testosterone administration increased impulsive choice. This finding supports the hypothesis that exogenous testosterone increases impulsivity among healthy young males in a laboratory task.
循环睾酮水平与冲动性呈正相关。本研究在一个跨期选择任务中考察了睾酮给药对冲动性的影响，在该任务中，参与者可以在较小的即时奖励和较大的延迟奖励之间做出选择。健康的年轻男性参与者（n=111）在一项双盲、安慰剂对照、被试间设计中接受了 150 毫克睾酮凝胶的单次剂量。在给药后 180 分钟，参与者进行了决策任务。无模型（即更高的无差异点）和基于模型（即更陡峭的折扣率）参数均表明，睾酮给药增加了冲动选择。这一发现支持了这样一种假设，即外源性睾酮会增加健康年轻男性在实验室任务中的冲动性。
