轮班和延长夜班工作对代谢综合征及其组成成分患病率的影响。

The effects of rotating and extended night shift work on the prevalence of metabolic syndrome and its components.

作者信息

Khosravipour Masoud, Shahmohammadi Mostafa, Athar Hossein Valadi

机构信息

Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Occupational Health Engineering, School of Public Health, Kermanshah University of Medical Science, Kermanshah, Iran; Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Department of Occupational Health Engineering, School of Public Health, Kermanshah University of Medical Science, Kermanshah, Iran; Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Diabetes Metab Syndr. 2019 Nov-Dec;13(6):3085-3089. doi: 10.1016/j.dsx.2019.11.006. Epub 2019 Nov 14.

DOI:10.1016/j.dsx.2019.11.006

PMID:31765983

Abstract

BACKGROUND

Some studies indicated night shift work can be associated with the higher risk of metabolic syndrome (MetS). However, the effect of both rotating and extended night shift work (12-hr rotating night) on MetS has not well-known. We aimed to examine and clarify the association among petrochemical workers.

METHODS

We recruited 1575 eligible workers in this study. According to shift work schedules the participants were divided into following groups: 12-hr fixed day and 12-hr rotating night. Biochemical data, including fasting blood sugar and lipid panel (TC, TG, LDL, and HDL) were determined by blood tests. Demographic data was obtained by interview at the time of blood pressure and anthropometric indices measurements. The National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) was applied to identify subjects with MetS. The Logistic regression models were used to predict risk of MetS and its components between study groups.

RESULTS

The prevalence of MetS was showed 18.4% (290/1575). We found a significant difference between study groups in the prevalence of MetS (p < 0.05). The odds ratios (ORs) and 95% confidence intervals (CIs) in the 12-hr rotating night group in comparison to the 12-hr fixed day shift group according to unadjusted and full adjusted logistic regression models were estimated 1.26 (0.96, 1.65) and 1.34 (1.01, 1.76), respectively. Among MetS components, we observed the significant higher risk in TG and HDL (P < 0.05).

CONCLUSION

This study suggests 12-hr rotating night shift as the high-risk group for MetS. More studies needed to confirm our findings.

摘要

背景

一些研究表明，夜班工作可能与代谢综合征（MetS）的较高风险相关。然而，轮班和延长夜班工作（12小时轮班制夜班）对代谢综合征的影响尚不清楚。我们旨在研究并阐明石化工人之间的这种关联。

方法

本研究招募了1575名符合条件的工人。根据轮班工作计划，参与者被分为以下几组：12小时固定白班和12小时轮班制夜班。通过血液检测确定生化数据，包括空腹血糖和血脂指标（总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白）。在测量血压和人体测量指标时，通过访谈获取人口统计学数据。采用美国国家胆固醇教育计划（NCEP）成人治疗小组第三次报告（ATP III）来确定患有代谢综合征的受试者。使用逻辑回归模型预测研究组之间代谢综合征及其组成部分的风险。

结果

代谢综合征的患病率为18.4%（290/1575）。我们发现研究组之间代谢综合征的患病率存在显著差异（p<0.05）。根据未调整和完全调整的逻辑回归模型，12小时轮班制夜班组与12小时固定白班组相比的优势比（OR）和95%置信区间（CI）分别估计为1.26（0.96，1.65）和1.34（1.01，1.76）。在代谢综合征的组成部分中，我们观察到甘油三酯和高密度脂蛋白的风险显著更高（P<0.05）。