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澳大利亚双胞胎研究:推动双胞胎研究的新范式。

Twins Research Australia: A New Paradigm for Driving Twin Research.

作者信息

Murphy Kate, Lam Janine, Cutler Tessa, Tyler Jess, Calais-Ferreira Lucas, Li Shuai, Little Callie, Ferreira Paulo, Craig Jeffrey M, Scurrah Katrina J, Hopper John L

机构信息

Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.

Department of Psychology, University of New England, Armidale, New South Wales, Australia.

出版信息

Twin Res Hum Genet. 2019 Dec;22(6):438-445. doi: 10.1017/thg.2019.101. Epub 2019 Nov 26.

DOI:10.1017/thg.2019.101
PMID:31767048
Abstract

Twins Research Australia (TRA) is a community of twins and researchers working on health research to benefit everyone, including twins. TRA leads multidisciplinary research through the application of twin and family study designs, with the aim of sustaining long-term twin research that, both now and in the future, gives back to the community. This article summarizes TRA's recent achievements and future directions, including new methodologies addressing causation, linkage to health, economic and educational administrative datasets and to geospatial data to provide insight into health and disease. We also explain how TRA's knowledge translation and exchange activities are key to communicating the impact of twin studies to twins and the wider community. Building researcher capability, providing registry resources and partnering with all key stakeholders, particularly the participants, are important for how TRA is advancing twin research to improve health outcomes for society. TRA provides researchers with open access to its vibrant volunteer membership of twins, higher order multiples (multiples) and families who are willing to consider participation in research. Established four decades ago, this resource facilitates and supports research across multiple stages and a breadth of health domains.

摘要

澳大利亚双胞胎研究组织(TRA)是一个由双胞胎和研究人员组成的团体,致力于开展健康研究,以使包括双胞胎在内的所有人受益。TRA通过应用双胞胎和家庭研究设计引领多学科研究,旨在维持长期的双胞胎研究,无论现在还是未来,都能回馈社区。本文总结了TRA最近的成就和未来方向,包括解决因果关系的新方法、与健康、经济和教育行政数据集以及地理空间数据的关联,以深入了解健康与疾病。我们还解释了TRA的知识转化和交流活动如何成为向双胞胎及更广泛社区传达双胞胎研究影响的关键。培养研究人员能力、提供登记资源以及与所有关键利益相关者(尤其是参与者)合作,对于TRA推进双胞胎研究以改善社会健康成果至关重要。TRA为研究人员提供开放获取其充满活力的双胞胎、高阶多胞胎(多胎)和愿意考虑参与研究的家庭志愿者成员的机会。该资源成立于四十年前,有助于并支持跨多个阶段和广泛健康领域的研究。

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