Sakhri L, Bertocchi M
Institut de cancérologie Daniel-Hollard, groupe hospitalier mutualiste de Grenoble, 8, rue Docteur-Calmette, 38028 Grenoble cedex 1, France.
Service de pneumologie, centre hospitalier Annecy Genevois, 1, avenue de l'Hôpital, 74374 Pringy, France.
Rev Mal Respir. 2019 Dec;36(10):1129-1138. doi: 10.1016/j.rmr.2018.06.013. Epub 2019 Nov 22.
Lung cancer remains the most lethal cancer. The most common cause is smoking, which is also preventable, unlike the causes of other types of cancer. A genetic characteristic has emerged over several years, which explains particular profiles of smokers, or highly dependent smokers. The emergence of new therapies for the treatment of lung cancer, and the impact of tobacco on reducing the effectiveness of these therapies must challenge practitioners to obtain a complete cessation of smoking regardless of the stage of the disease.
肺癌仍然是最致命的癌症。最常见的病因是吸烟，与其他类型癌症的病因不同，吸烟是可以预防的。多年来出现了一种基因特征，它解释了吸烟者或高度依赖吸烟者的特定情况。肺癌新治疗方法的出现，以及烟草对降低这些治疗方法有效性的影响，必然促使从业者无论疾病处于何种阶段，都要让患者完全戒烟。
