Pascha J, Frings A, Walochnik J, Wissiak E, Dirisamer M, Daas L, Ardjomand N
Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Deutschland.
Universitätsaugenklinik Düsseldorf, Düsseldorf, Deutschland.
Ophthalmologe. 2020 Sep;117(9):926-929. doi: 10.1007/s00347-019-01013-4.
Diagnosis of acanthamoeba keratitis is often a clinical challenge. In most cases it is primarily confused with herpes keratitis. A coinfection with bacteria or fungi can also lead to a delayed diagnosis and initiation of treatment. A few cases reported the detection of acanthamoeba in the anterior chamber. In the case of endophthalmitis without the detection of bacteria or fungi acanthamoeba should therefore always be considered as a potential differential diagnosis. The local and systemic administration of voriconazole can be successfully used to treat acanthamoeba endophthalmitis.
棘阿米巴角膜炎的诊断常常是一项临床挑战。在大多数情况下,它主要与疱疹性角膜炎相混淆。细菌或真菌感染也可能导致诊断延迟和治疗开始时间推迟。有少数病例报告在前房中检测到棘阿米巴。因此,在未检测到细菌或真菌的眼内炎病例中,应始终将棘阿米巴视为一种潜在的鉴别诊断。伏立康唑的局部和全身给药可成功用于治疗棘阿米巴性眼内炎。