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一名肾移植患者在治疗皮肤病期间发生棘阿米巴性眼内炎。

Acanthamoeba endophthalmitis during treatment for cutaneous disease in a renal transplant patient.

作者信息

Kutner Allison, Aldrich Margaret, Patel Sarju, Kang Joann J, Amin Bijal, Mann Ranon, Ali Ibne Karim M, Martines Roosecelis Brasil, Cope Jennifer Rittenhouse, De Boccardo Graciela O, Puius Yoram A

机构信息

Department of Dermatology, Montefiore Medical Center, Bronx, NY, USA.

Division of Infectious Diseases, Department of Medicine, Montefiore Medical Center, Bronx, NY, USA.

出版信息

Transpl Infect Dis. 2018 Apr;20(2):e12843. doi: 10.1111/tid.12843. Epub 2018 Feb 12.

Abstract

Acanthamoeba infections are difficult to diagnose and treat. We present a renal transplant patient who developed Acanthamoeba endophthalmitis on therapy with posaconazole and miltefosine for cutaneous acanthamobiasis. The patient was maintained on intracameral voriconazole injections, and oral azithromycin, fluconazole, and flucytosine. This case highlights novel presentations and treatments for acanthamoebic infection.

摘要

棘阿米巴感染难以诊断和治疗。我们报告了一名肾移植患者,该患者在接受泊沙康唑和米替福新治疗皮肤棘阿米巴病时发生了棘阿米巴性眼内炎。患者持续接受前房内注射伏立康唑以及口服阿奇霉素、氟康唑和氟胞嘧啶治疗。该病例突出了棘阿米巴感染的新表现和治疗方法。

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