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改良Ivor-Lewis手术在食管胃交界部Siewert II型腺癌中的临床应用与观察

Clinical application and observation of modified Ivor-Lewis surgery in Siewert type II adenocarcinoma of the Esophagogastric junction.

作者信息

Yin Qifan, Wang Wenhao, Liu Huining, Yang Guang, Zhou Shaohui, Liu Lijun

机构信息

Department of Thoracic Surgery, Hebei General Hospital, 348, West He-Ping Road, Shijiazhuang, 050051, Hebei Province, People's Republic of China.

出版信息

J Cardiothorac Surg. 2019 Nov 27;14(1):207. doi: 10.1186/s13019-019-1023-7.

Abstract

BACKGROUND

The surgical approach (transthoracic or transabdominal) for patients with Siewert type II adenocarcinoma of the esophagogastric junction (AEG) still remains controversial. We made a bold attempt to adopt the modified Ivor-Lewis surgery, No turning over, thoraco-laparoscopic esophagogastrectomy, two-field lymphadenectomy and intrathoracic anastomosis, to observe the clinical application and effect.

METHOD

Data of patients with Siewert type II AEG were collected in the Hebei General Hospital from June 2017 to February 2019. The operation time, surgical blood loss, the number of dissected lymph nodes, duration of drainage tube, postoperative complications, the length of postoperative hospital stay were collected to assess the safety and feasibility of modified Ivor-Lewis surgery.

RESULTS

A total of 20 patients with Siewert type II AEG were analyzed in our research, there was no case of turning to thoracotomy, laparotomy or death during the operation.The average operation time, surgical blood loss, amount of dissected lymph nodes, duration of drainage tube, postoperative hospital stay of all enrolled patients was 4.67, 0.57 h, 156, 56.80 ml, 22.55, 3.91, 8.6, 2.21 days, 12.85, 2.5 days respectively. Among all the enrolled patients, one patient(5%) developed anastomotic fistula and one patient(5%) developed hematemesis after operation, eventually, these two patients were discharged successfully.

CONCLUSION

For patients with Siewert type II AEG, The modified Ivor-Lewis surgery, No turning over, thoraco-laparoscopic esophagogastrectomy, two-field lymphadenectomy and intrathoracic anastomosis, is safe and feasible. The feasibility and safety could be further and better investigated with a RCT to achieve more conclusive results.

摘要

背景

对于食管胃交界部(AEG)Siewert II型腺癌患者的手术入路(经胸或经腹)仍存在争议。我们大胆尝试采用改良的Ivor-Lewis手术,即不翻转、胸腹腔镜联合食管胃切除术、两野淋巴结清扫术及胸内吻合术,以观察其临床应用及效果。

方法

收集2017年6月至2019年2月在河北医科大学第一医院接受治疗的Siewert II型AEG患者的数据。记录手术时间、术中出血量、清扫淋巴结数目、引流管留置时间、术后并发症及术后住院时间,以评估改良Ivor-Lewis手术的安全性和可行性。

结果

本研究共纳入20例Siewert II型AEG患者,术中无一例转为开胸、开腹或死亡。所有纳入患者的平均手术时间、术中出血量、清扫淋巴结数目、引流管留置时间、术后住院时间分别为4.67、0.57小时,156、56.80毫升,22.55、3.91天,8.6、2.21天,12.85、2.5天。所有纳入患者中,1例(5%)术后发生吻合口瘘,1例(5%)术后发生呕血,最终这2例患者均顺利出院。

结论

对于Siewert II型AEG患者,改良的Ivor-Lewis手术,即不翻转、胸腹腔镜联合食管胃切除术、两野淋巴结清扫术及胸内吻合术,是安全可行的。通过随机对照试验可进一步更好地研究其可行性和安全性,以获得更具结论性的结果。

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