Lindsay D S, Blagburn B L, Sundermann C A, Giambrone J J
Department of Pathology and Parasitology, College of Veterinary Medicine, Auburn University, AL 36849.
Am J Vet Res. 1988 Aug;49(8):1412-4.
Clinical signs of respiratory tract disease were observed in chickens that were inoculated intratracheally with 1 x 10(6) oocysts of Cryptosporidium baileyi at 2 or 14 days of age (10 chickens/group), but not in chickens inoculated at 28 or 42 days of age (10 chickens/group). Orally inoculated chickens in all age groups (10 chickens/group) did not develop clinical signs of disease. Orally and intratracheally inoculated chickens in all age groups were infected, as determined by the finding of cryptosporidia in tissue sections of the trachea, bursa of Fabricius, and cloaca, and by the recovery of oocysts from their feces. Chickens inoculated at 2 and 14 days of age excreted oocysts for a longer period and had greater numbers of cryptosporidia in their tissues, compared with chickens inoculated at 28 and 42 days of age.
在2日龄或14日龄时经气管接种1×10⁶个贝利隐孢子虫卵囊的鸡（每组10只鸡）出现了呼吸道疾病的临床症状，但在28日龄或42日龄接种的鸡（每组10只鸡）中未观察到此类症状。所有年龄组经口接种的鸡（每组10只鸡）均未出现疾病的临床症状。通过在气管、法氏囊和泄殖腔组织切片中发现隐孢子虫以及从粪便中回收卵囊确定，所有年龄组经口和经气管接种的鸡均被感染。与28日龄和42日龄接种的鸡相比，2日龄和14日龄接种的鸡排出卵囊的时间更长，组织中的隐孢子虫数量更多。
