International Center for Hip, Knee and Foot Surgery (HKF), ATOS Clinic Heidelberg, Bismarckstr. 9-15, 69115, Heidelberg, Germany.
Complex Joint Reconstruction Center, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Knee Surg Sports Traumatol Arthrosc. 2020 Jul;28(7):2309-2315. doi: 10.1007/s00167-019-05801-y. Epub 2019 Nov 28.
To investigate the clinical outcome of autologous matrix-induced chondrogenesis (AMIC) implementation for mid-sized chondral lesions of the acetabulum in young active patients, and assess their potential to resume an active lifestyle including return to recreational athletic activities.
Sixty-two patients with full-thickness mid-sized acetabular chondral lesions were studied. All patients who underwent an arthroscopic AMIC procedure for reconstruction of chondral defects were assessed pre-operatively and at least 2 years post-operatively using the Hip disability and Osteoarthritis Outcome Score (HOOS), modified Harris Hip Score (mHHS) and Visual Analog Scale (VAS) for pain.
A significant improvement in all three scores at the time of follow-up was found. The mean HOOS improved from 58.8 ± 7.4 pre-operatively to 90.6 ± 7.1 at follow-up (p < 0.001) while the mean mHHS improved from 53.4 ± 6.6 to 82.4 ± 8.2 (p < 0.001). There was a significant decrease from 4.9 ± 1.1 pre-operatively to 1.1 ± 0.8 post-operatively (p < 0.001) in the VAS pain evaluation, indicating that the patients were satisfied with their relief of pain.
The AMIC procedure is an effective single-stage technique for the reconstruction of mid-size chondral defects of acetabulum in amateur athletes. This intervention enhanced the potential for patients to resume recreational athletic activities and the 2-year clinical outcome as evaluated by the HOOS, mHHS and VAS showed significant improvement over the pre-operative evaluations.
研究自体基质诱导软骨生成(AMIC)治疗年轻活跃患者髋关节中型软骨病变的临床疗效,并评估其恢复积极生活方式(包括重返娱乐性运动活动)的潜力。
研究了 62 例全层髋关节中型软骨病变患者。所有接受关节镜 AMIC 手术重建软骨缺损的患者均在术前和术后至少 2 年进行髋关节残疾和骨关节炎结果评分(HOOS)、改良 Harris 髋关节评分(mHHS)和疼痛视觉模拟评分(VAS)评估。
随访时发现所有 3 项评分均显著改善。HOOS 平均从术前的 58.8±7.4 分提高到术后的 90.6±7.1 分(p<0.001),mHHS 从 53.4±6.6 分提高到 82.4±8.2 分(p<0.001)。VAS 疼痛评估从术前的 4.9±1.1 分降至术后的 1.1±0.8 分(p<0.001),表明患者对疼痛缓解感到满意。
AMIC 手术是治疗业余运动员髋关节中型软骨缺损的一种有效单阶段技术。这种干预增强了患者恢复娱乐性运动活动的潜力,HOOS、mHHS 和 VAS 的 2 年临床结果显示,与术前评估相比,有显著改善。