Research Center of the Sainte-Justine University Hospital, Montreal, Quebec, Canada H3T 1C5; Department of Nutrition, Faculty of Medicine, Université de Montreal, Montreal, Quebec, Canada H3T 1J4.
Research Center of the Sainte-Justine University Hospital, Montreal, Quebec, Canada H3T 1C5; Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Research Center of the Sainte-Justine University Hospital, 3175 Côte Ste-Catherine room 4.17.006, Montreal, Quebec, Canada H3T 1C5.
Spine J. 2020 May;20(5):785-799. doi: 10.1016/j.spinee.2019.11.012. Epub 2019 Nov 26.
Some studies have shown that patients with adolescent idiopathic scoliosis (AIS) have different anthropometric features compared with their peers such as taller stature, lower body mass index, and bone mineral density. Yet the causes explaining these differences remain uncertain. Nutritional intake and status, combined with physical activity, could explain these discrepancies. We aimed to review the current literature on energy and nutrient intake, on nutritional status and physical activity in relation to AIS and to discuss study methodologies and propose avenues for future studies. Studies describing energy or nutrient intake in AIS mostly focused on total energy and calcium and found no difference between AIS and control cohorts. Regarding nutritional status, it was found that AIS patients have lower vitamin D levels than controls and that most patients have insufficient or deficient vitamin D serum levels. Lower concentration of parathyroid hormones and calcitonin were also found in AIS compared to controls as well as anomalies in trace elements. In the studies that have assessed physical activity, three found that AIS girls were less active than controls, but four did not observe differences between groups. In this review, we highlight that nutrition and physical activity are important topics in AIS that require further research as they could help understand anthropometric discrepancies and disease etiology.
一些研究表明,与同龄人相比,青少年特发性脊柱侧凸(AIS)患者具有不同的人体测量特征,例如身高较高、体重指数较低和骨密度较低。然而,导致这些差异的原因仍不确定。营养摄入和状况,加上身体活动,可能可以解释这些差异。我们旨在回顾关于 AIS 相关的能量和营养素摄入、营养状况和身体活动的当前文献,并讨论研究方法学,为未来的研究提出方向。描述 AIS 中能量或营养素摄入的研究大多集中在总能量和钙上,并未发现 AIS 与对照组之间存在差异。关于营养状况,发现 AIS 患者的维生素 D 水平低于对照组,并且大多数患者的维生素 D 血清水平不足或缺乏。与对照组相比,AIS 患者的甲状旁腺激素和降钙素浓度也较低,以及微量元素异常。在评估身体活动的研究中,有三项发现 AIS 女孩比对照组不活跃,但四项研究并未观察到组间差异。在本综述中,我们强调指出,营养和身体活动是 AIS 中的重要课题,需要进一步研究,因为它们可以帮助了解人体测量差异和疾病病因。