Helliwell P S, Howe A, Wright V
University Department of Medicine, General Infirmary, Leeds.
Ann Rheum Dis. 1988 Sep;47(9):754-8. doi: 10.1136/ard.47.9.754.
Metacarpophalangeal joint stiffness was measured using a new microprocessor controlled arthrograph in 135 patients with rheumatoid arthritis. Subjects were prospectively subdivided according to the stage of the disease in the joint. Compared with a normal population stiffness variables in active rheumatoid arthritis were decreased, significantly so for non-elastic stiffness. This study casts doubts on the literal interpretation of symptomatic stiffness as an indicator of disease activity in rheumatoid arthritis and suggests a number of explanations for the discordant result.
使用一种新型微处理器控制的关节造影仪对135例类风湿性关节炎患者的掌指关节僵硬情况进行了测量。根据关节疾病的阶段对受试者进行前瞻性分组。与正常人群相比，活动期类风湿性关节炎的僵硬变量有所降低，非弹性僵硬的降低尤为显著。这项研究对将症状性僵硬直接解读为类风湿性关节炎疾病活动指标提出了质疑，并对这一不一致的结果给出了一些解释。
