National Research and Development Center for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, PR China.
National Research and Development Center for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, PR China.
J Hazard Mater. 2020 Apr 15;388:121728. doi: 10.1016/j.jhazmat.2019.121728. Epub 2019 Nov 20.
The solvated mercuric ion (Hg) from industrial pollutants are highly toxic to the ecological environment and human health. Driven by urgent need for the selective and sensitive detection of Hg, a magnetic relaxation switching (MRS) based on FeO nanoparticles (NPs) was designed. Practically, the concentrations of Hg in industrial pollutant is usually much higher than the detection range. Thus, gold nanoparticles (AuNPs) were synthesized on the surface of FeO NPs to enable the visual detection of Au@FeO NPs. The presence of Hg in sample can specifically cause the aggregation of Au@FeO-aptamers NPs through T-Hg-T base pairs, leading to the change in transverse relaxation time T value of detection solution. The MRS sensor showed excellent response for Hg ions in the range of 10 nM-100 nM and 100 nM to 5 μM. A highly sensitive and selective measurement of Hg was obtained with a limit of detection of 2.7 nM. Noticeably, the visual detection can qualitatively analyze the Hg beyond 5 μM by naked eye without advanced instrumentation and skilled operators.
工业污染物中溶解的汞离子（Hg）对生态环境和人类健康具有高度毒性。受选择性和灵敏检测 Hg 的迫切需求驱动，设计了一种基于 FeO 纳米粒子（NPs）的磁弛豫切换（MRS）。实际上，工业污染物中 Hg 的浓度通常远高于检测范围。因此，在 FeO NPs 表面合成了金纳米粒子（AuNPs），以实现 Au@FeO NPs 的可视化检测。样品中 Hg 的存在可以通过 T-Hg-T 碱基对特异性引起 Au@FeO-适体 NPs 的聚集，导致检测溶液的横向弛豫时间 T 值发生变化。MRS 传感器在 10 nM-100 nM 和 100 nM-5 μM 范围内对 Hg 离子表现出优异的响应。检测到的 Hg 具有 2.7 nM 的低检测限，实现了高灵敏度和选择性的测量。值得注意的是，无需先进的仪器和熟练的操作人员，通过肉眼就可以对超过 5 μM 的 Hg 进行定性分析。
