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鱼油对高胆固醇饮食家兔动脉粥样硬化形成及血小板生成的影响。

The effect of fish oil on atherogenesis and thrombopoiesis in rabbits on high cholesterol diet.

作者信息

Kristensen S D, Roberts K M, Lawry J, Martin J F

机构信息

University Department of Medicine, Royal Hallamshire Hospital, Sheffield, U.K.

出版信息

Artery. 1988;15(5):250-8.

PMID:3178501
Abstract

The effect of fish oil supplementation on atherogenesis and thrombopoiesis was investigated in rabbits fed a high cholesterol diet for 7 weeks. There was no statistically significant difference between the area of lipid accumulation in the aorta of the animals fed fish oil and the control animals. There was no statistically significant difference in platelet count, mean platelet volume, megakarycoyte DNA content or serum cholesterol between the two groups. Serum triglyceride was significantly higher in the fish oil group than in the controls (p less than 0.035). Fish oil supplementation does not change atherogenesis or thrombopoiesis in the cholesterol fed rabbit.

摘要

在喂食高胆固醇饮食7周的兔子中研究了补充鱼油对动脉粥样硬化形成和血小板生成的影响。喂食鱼油的动物与对照动物的主动脉脂质积累面积之间没有统计学上的显著差异。两组之间的血小板计数、平均血小板体积、巨核细胞DNA含量或血清胆固醇没有统计学上的显著差异。鱼油组的血清甘油三酯显著高于对照组(p小于0.035)。补充鱼油不会改变喂食胆固醇的兔子的动脉粥样硬化形成或血小板生成。

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