Rowett Institute, University of Aberdeen, Ashgrove Road West, Aberdeen, AB25 2ZD, UK.
Medical Statistics Team, Division of Applied Health Sciences, Polwarth Building University of Aberdeen Foresterhill, Aberdeen, AB25 2ZD, UK.
Hernia. 2020 Aug;24(4):793-800. doi: 10.1007/s10029-019-02073-w. Epub 2019 Nov 30.
Laparoscopic (LHR) and open (OHR) inguinal hernia repairs are both used to treat primary herniae. This study analyses the rates of operation for recurrence after laparoscopic and open inguinal hernia repair, at a population level, while considering competing risks, such as death and other operative interventions.
This is a population cohort study in Scotland. All adult patients who had a primary inguinal hernia repair in Scotland between 01/04/1996 and 01/01/2015 were included. The main outcome was recurrent operations. Cumulative incidence functions (CIF) were calculated for competing risks of death. A cox proportional hazards regression model was used to control for confounders of age, gender, bilateral herniae, deprivation and year of procedure.
Of 88,590 patients, there were 10,145 LHR and 78,445 OHR. Recurrent operations were required in 1397 (1.8%) OHR and 362 (3.6%). LHR had greater hazard of recurrence than OHR (HR 1.83, 95% CI 1.61-2.08, p < 0.001). Faster time to recurrence was also associated with being older (HR for one year increase: 1.010, 95% CI 1.007-1.013, p < 0.001), being more affluent (HR 1.18, 95% CI 1.01-1.38, p = 0.04) and having a bilateral index operation (HR 2.53, 95% CI 2.22-2.88, p < 0.001).
LHR is becoming more popular in Scotland over the past 2 decades. However, when other key confounding factors are controlled, it is associated with a higher recurrence rate.
腹腔镜(LHR)和开放式(OHR)腹股沟疝修补术均可用于治疗原发性疝。本研究在考虑死亡和其他手术干预等竞争风险的情况下,分析了人群水平上腹腔镜和开放式腹股沟疝修补术后复发的手术率。
这是苏格兰的一项人群队列研究。纳入了 1996 年 4 月 1 日至 2015 年 1 月 1 日期间在苏格兰接受原发性腹股沟疝修补术的所有成年患者。主要结局是再次手术。计算了死亡等竞争风险的累积发病率函数(CIF)。使用 Cox 比例风险回归模型控制年龄、性别、双侧疝、贫困程度和手术年份等混杂因素。
在 88590 例患者中,有 10145 例 LHR 和 78445 例 OHR。78445 例 OHR 中有 1397 例(1.8%)和 10145 例 LHR 中有 362 例(3.6%)需要再次手术。LHR 的复发风险高于 OHR(HR 1.83,95%CI 1.61-2.08,p<0.001)。复发时间更快也与年龄较大(每增加一年的 HR:1.010,95%CI 1.007-1.013,p<0.001)、较富裕(HR 1.18,95%CI 1.01-1.38,p=0.04)和索引手术为双侧(HR 2.53,95%CI 2.22-2.88,p<0.001)有关。
在过去 20 年中,LHR 在苏格兰越来越受欢迎。然而,当控制其他关键混杂因素时,它与更高的复发率相关。