Department of Structural Heart Disease, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, PR China.
Department of Gastroenterology, the First Affiliated Hospital of Jilin University, Changchun 130000, PR China.
Future Oncol. 2019 Dec;15(36):4207-4222. doi: 10.2217/fon-2019-0473. Epub 2019 Dec 2.
To build a prognostic nomogram based on log odds of positive lymph nodes for patients with gastric carcinoma (GC) after resection, and to compare the predictive performance with the American Joint Committee on Cancer (AJCC) staging system and lymph node ratio (LNR). Multivariate analyses were performed to identify the independent variables for cancer-specific survival (CSS). A nomogram was constructed based on independent clinicopathological factors. The C-indices for predicting CSS were 0.674 in development cohort and 0.647 in validation cohort, which were higher than that of the AJCC staging system and LNR. The nomogram was more accurate than the AJCC staging system and LNR for predicting CSS in patients undergoing resection for GC.
为了建立一个基于胃癌（GC）患者淋巴结阳性对数优势的预后列线图，并与美国癌症联合委员会（AJCC）分期系统和淋巴结比率（LNR）进行预测性能比较，对多变量分析进行了识别癌症特异性生存（CSS）的独立变量。基于独立的临床病理因素构建了一个列线图。发展队列中预测 CSS 的 C 指数为 0.674，验证队列中为 0.647，高于 AJCC 分期系统和 LNR。对于接受 GC 切除术的患者，列线图在预测 CSS 方面比 AJCC 分期系统和 LNR 更准确。
