Porto Ana Carolina Souza, Blumetti Tatiana Pinto, Macedo Mariana Petaccia de, Braga Juliana Casagrande Tavoloni
Cutaneous Oncology Department, AC Camargo Cancer Center, São Paulo, SP, Brazil.
Cutaneous Oncology Department, AC Camargo Cancer Center, São Paulo, SP, Brazil.
An Bras Dermatol. 2019 Nov-Dec;94(6):747-750. doi: 10.1016/j.abd.2019.01.002. Epub 2019 Oct 26.
Melanoacanthoma is a rare variant of seborrheic keratosis, which is notable for dark pigmentation and fast radial growth, making it difficult to distinguish from melanoma. Histologically, it is characterized by proliferation of keratinocytes and dendritic melanocytes. The authors report a scalp lesion, fast growing, suspected by dermoscopy and confocal microscopy examination, with dendritic cells distributed throughout the lesion. Based on these findings, it was not possible to classify this lesion as clearly benign, so it was excised. Histopathologic evaluation and immunostain were consistent with melanoacanthoma.
黑素棘皮瘤是脂溢性角化病的一种罕见变体，其以色素沉着深和快速的径向生长为显著特征，这使得它难以与黑色素瘤区分开来。在组织学上，其特征为角质形成细胞和树突状黑素细胞的增殖。作者报告了一例头皮病变，生长迅速，经皮肤镜和共聚焦显微镜检查怀疑为此病，病变内可见树突状细胞分布。基于这些发现，无法将该病变明确分类为良性，因此将其切除。组织病理学评估和免疫染色结果与黑素棘皮瘤相符。
