Shankar Vikas, Nandi Jayoti, Ghosh Kisalay, Ghosh Sanjay
Department of Dermatology, Venerology, Leprology, M.G.M. Medical College and L.S.K. Hospital, Kishanganj, Bihar, India.
Indian J Dermatol. 2011 Jan;56(1):79-81. doi: 10.4103/0019-5154.77559.
Melanoacanthoma denotes a rare variant of pigmented seborrheic keratosis. A 65-year-old male farmer had pigmented, verrucous, itchy, highly painful, progressively growing irregularly oval plaque on left side of lower back for the past five years. The indurated lesion, measuring maximum diameter 10 cm × 5 cm, had no discharge, bleeding, ulceration, or associated lymphadenopathy. Dermoscopy showed regular pigmentary network and cribiform pattern of ridges without any feature of malignant melanoma. Histopathology showed well-defined islands of basaloid cells interspersed with large and richly dendritic melanocytes. The lesion was totally excised followed by skin grafting. Our patient was unique in its massive size and clinical resemblance with malignant melanoma. The diagnosis was confirmed by dermoscopy and skin biopsy.
黑素棘皮瘤是色素性脂溢性角化病的一种罕见变异型。一名65岁男性农民，在过去五年中，其左下背部左侧出现了一个色素沉着、疣状、瘙痒、剧痛、逐渐生长的不规则椭圆形斑块。该硬结性病变最大直径为10 cm×5 cm，无分泌物、出血、溃疡或相关淋巴结肿大。皮肤镜检查显示有规则的色素网和筛状嵴纹模式，无任何恶性黑素瘤特征。组织病理学显示基底样细胞岛界限清晰，其间散布着大量且富含树枝状突起的黑素细胞。病变被完全切除，随后进行了皮肤移植。我们的患者病变体积巨大，临床特征与恶性黑素瘤相似，较为独特。诊断通过皮肤镜检查和皮肤活检得以证实。
