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使用阿达木单抗的强直性脊柱炎患者出现小叶性毛细血管瘤:一种表现旺盛的情况。

Lobular capillary hemangioma in a patient with ankylosing spondylitis using adalimumab: an exuberant presentation.

作者信息

Silva Thadeu Santos, Guimarães Carlos Leonardo Martins, Xavier Isabela Pimenta, Rego Vitória Regina Pedreira de Almeida

机构信息

Dermatology Service, Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil; Teaching and Care Outpatient Clinic, Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.

Pathology Service, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, BA, Brazil.

出版信息

An Bras Dermatol. 2019 Nov-Dec;94(6):751-753. doi: 10.1016/j.abd.2019.02.004. Epub 2019 Oct 26.

DOI:10.1016/j.abd.2019.02.004
PMID:31789263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6939071/
Abstract

Lobular capillary hemangioma or pyogenic granuloma is a benign vascular tumor of the skin or mucous membranes. Most patients present a single lesion. It manifests clinically as an erythematous, friable, and fast-growing tumor. This report details a case with exuberant presentation in a patient with ankylosing spondylitis, using adalimumab. Factors triggering pyogenic granuloma are not well known. They may spontaneously regress, but most require treatment.

摘要

小叶性毛细血管瘤或化脓性肉芽肿是一种皮肤或黏膜的良性血管肿瘤。大多数患者表现为单个病灶。临床上表现为红斑、易碎且生长迅速的肿瘤。本报告详细介绍了一例使用阿达木单抗的强直性脊柱炎患者出现的典型病例。引发化脓性肉芽肿的因素尚不清楚。它们可能会自行消退,但大多数需要治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/436175e97ce6/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/b7f1bf34635a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/43bfa0d72b75/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/c80ca6e4379b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/436175e97ce6/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/b7f1bf34635a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/43bfa0d72b75/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/c80ca6e4379b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d28e/6939071/436175e97ce6/gr4.jpg

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本文引用的文献

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Paradoxical psoriasis after the use of anti-TNF in a patient with rheumatoid arthritis.一名类风湿关节炎患者使用抗TNF药物后出现矛盾性银屑病。
An Bras Dermatol. 2016 Sep-Oct;91(5 suppl 1):137-139. doi: 10.1590/abd1806-4841.20164456.
2
Pyogenic granuloma association with isotretinoin treatment for acne.化脓性肉芽肿与异维A酸治疗痤疮的相关性。
Australas J Dermatol. 2016 Nov;57(4):e144-e145. doi: 10.1111/ajd.12418.
3
Pyogenic Granuloma in a Patient on Gefitinib.一名服用吉非替尼的患者发生化脓性肉芽肿。
Acta Med Port. 2016 Jun;29(6):416. doi: 10.20344/amp.6343. Epub 2016 Jun 30.
4
Pyogenic granuloma possibly associated with capecitabine therapy.化脓性肉芽肿可能与卡培他滨治疗有关。
J Dermatol. 2017 Nov;44(11):1329-1331. doi: 10.1111/1346-8138.13691. Epub 2016 Nov 18.
5
Pyogenic granuloma caused by afatinib: Case report and review of the literature.阿法替尼所致化脓性肉芽肿:病例报告及文献复习
Australas J Dermatol. 2017 Feb;58(1):61-62. doi: 10.1111/ajd.12423. Epub 2015 Nov 25.
6
Periungual and subungual pyogenic granuloma following anti-TNF-α therapy: is it the first case?抗 TNF-α 治疗后甲周和甲下脓性肉芽肿:这是首例吗?
Dermatol Ther. 2013 Nov-Dec;26(6):493-5. doi: 10.1111/dth.12022. Epub 2013 Apr 1.
7
Pyogenic granuloma - the quest for optimum treatment: audit of treatment of 408 cases.化脓性肉芽肿——寻求最佳治疗方法:408例治疗情况审计
J Plast Reconstr Aesthet Surg. 2007;60(9):1030-5. doi: 10.1016/j.bjps.2006.10.018. Epub 2007 May 2.