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诊断病例。脱氧胆酸盐中胚层疗法诱发的非感染性化脓性脂膜炎。

Case for diagnosis. Noninfectious suppurative panniculitis induced by mesotherapy with deoxycholate.

作者信息

Campos Luana Moraes, Miot Luciane Donida Bartoli, Marques Mariângela Esther Alencar, Miot Hélio Amante

机构信息

Department of Dermatology and Radiotherapy, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brazil.

Service of Pathology, Departamento de Patologia, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brazil.

出版信息

An Bras Dermatol. 2019 Nov-Dec;94(6):754-756. doi: 10.1016/j.abd.2019.02.003. Epub 2019 Oct 24.

DOI:10.1016/j.abd.2019.02.003
PMID:31789264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6939069/
Abstract

A 28-year-old white female patient presented with multiple erythematous-to-violaceous, painful, suppurative nodules on the buttocks and thighs that appeared after two weeks of mesotherapy with deoxycholate, caffeine, sunflower liposomes, and sinetrol for localized fat. She was treated for atypical mycobacteriosis, but with no satisfactory response after antibiotic therapy. Bacterial, mycobacterial, and fungal culture were all negative. Histopathologic examination of the biopsy showed noninfectious suppurative panniculitis. It resolved after treatment with methotrexate, prednisone, and hydroxychloroquine. This report highlights the rarity of this complication, the importance of its early recognition, and differentiation with atypical fast growing mycobacterioses.

摘要

一名28岁的白人女性患者,在接受脱氧胆酸盐、咖啡因、葵花籽脂质体和sinetrol局部脂肪溶脂疗法两周后,臀部和大腿出现多个从红斑到紫蓝色、疼痛的化脓性结节。她接受了非典型分枝杆菌病的治疗,但抗生素治疗后效果不佳。细菌、分枝杆菌和真菌培养均为阴性。活检的组织病理学检查显示为非感染性化脓性脂膜炎。经甲氨蝶呤、泼尼松和羟氯喹治疗后病情缓解。本报告强调了这种并发症的罕见性、早期识别的重要性以及与非典型快速生长分枝杆菌病的鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/5b476d86de5c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/f5a6b4d2e786/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/9f9f5be297c1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/5b476d86de5c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/f5a6b4d2e786/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/9f9f5be297c1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014f/6939069/5b476d86de5c/gr3.jpg

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Disseminated cutaneous atypical mycobacteriosis by M. chelonae after sclerotherapy of varicose veins in a immunocompetent patient: a case report.免疫功能正常患者静脉曲张硬化治疗后发生龟分枝杆菌播散性皮肤非典型分枝杆菌病:一例报告
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Mesotherapy for local fat reduction.中胚层疗法用于局部减脂。
Obes Rev. 2013 Oct;14(10):780-91. doi: 10.1111/obr.12049. Epub 2013 Jun 25.
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Induction of fat cell necrosis in human fat tissue after treatment with phosphatidylcholine and deoxycholate.
用磷脂酰胆碱和脱氧胆酸钠处理人脂肪组织后诱导脂肪细胞坏死。
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Mixed cell granulomatous panniculitis on the cheek due to injection of a solution containing phosphatidylcholine and deoxycholate.因注射含磷脂酰胆碱和脱氧胆酸盐的溶液导致脸颊出现混合细胞性肉芽肿性脂膜炎。
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A complication of mesotherapy: noninfectious granulomatous panniculitis.中胚层疗法的一种并发症:非感染性肉芽肿性脂膜炎。
Arch Dermatol. 2008 Jun;144(6):808-9. doi: 10.1001/archderm.144.6.808.
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Detergent effects of sodium deoxycholate are a major feature of an injectable phosphatidylcholine formulation used for localized fat dissolution.脱氧胆酸钠的去污作用是一种用于局部脂肪溶解的注射用磷脂酰胆碱制剂的主要特性。
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