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抗休克裤充气对犬模型低温性心血管抑制的影响。

The effects of antishock trouser inflation during hypothermic cardiovascular depression in the canine model.

作者信息

Kolodzik P W, Mullin M J, Krohmer J R, McCabe J B

机构信息

Department of Emergency Medicine, Wright State University School of Medicine, Dayton, OH 45401.

出版信息

Am J Emerg Med. 1988 Nov;6(6):584-90. doi: 10.1016/0735-6757(88)90096-4.

Abstract

The purpose of this study was to investigate the value and to identify any deleterious effects of antishock trouser use during hypothermic cardiovascular depression. Thirteen mongrels were made hypotensive by cooling to a core temperature of approximately 27 degrees C. Eight dogs had antishock trousers inflated for one hour and five dogs served as controls. Metabolic and hemodynamic variables were measured at regular intervals during cooling, during trouser inflation, and after trouser deflation. No study animal experienced ventricular fibrillation. Neither central temperature, pH, or serum potassium nor mean arterial BP or systemic vascular resistance were significantly affected by trouser inflation or deflation. Antishock trouser use during the early phase of hypothermia before rewarming does not appear to result in a central bolus of cold, acidotic, hyperkalemic blood or the precipitation of ventricular fibrillation. There appears to be no significant hemodynamic benefit of antishock trouser use early in the management of hypotension caused by moderate hypothermia.

摘要

本研究的目的是探讨抗休克裤在低温性心血管抑制期间的价值,并确定其任何有害影响。将13只杂种犬冷却至核心体温约27摄氏度,使其血压降低。8只犬的抗休克裤充气1小时,5只犬作为对照。在降温期间、裤子充气期间和裤子放气后定期测量代谢和血流动力学变量。没有实验动物发生心室颤动。裤子充气或放气对中心温度、pH值、血清钾、平均动脉血压或全身血管阻力均无显著影响。在复温前的低温早期使用抗休克裤似乎不会导致中心性冷的、酸中毒的、高钾血症的血液团块或心室颤动的发生。在中度低温引起的低血压早期处理中,使用抗休克裤似乎没有显著的血流动力学益处。

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