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用于肌肉骨骼疾病治疗的干细胞 - 矫形/运动医学应用。

Stem Cells for Treatment of Musculoskeletal Conditions - Orthopaedic/Sports Medicine Applications.

机构信息

Texas Tech University Health Sciences Center, Department of Orthopaedic Surgery, 3601 4(th) Street STOP 9436, Lubbock, TX 79430 United States of America.

Texas Tech University, 1301 Akron Avenue, Lubbock, TX 79409 United States of America.

出版信息

Biochim Biophys Acta Mol Basis Dis. 2020 Apr 1;1866(4):165624. doi: 10.1016/j.bbadis.2019.165624. Epub 2019 Nov 30.

Abstract

A myriad of musculoskeletal conditions afflicts a vast number of the world's population from birth to death. Countless pathological diseases and traumatic injuries (acute and chronic) contribute to different human disabilities, causing a tremendous financial toll on the economy of healthcare. The medical field is continually searching for novel ways to combat orthopedically related conditions. The immediate goal is the restoration of anatomy then ultimately return of function in hopes of enhancing quality if not the quantity of life. Traditional methods involve surgical correction/reconstruction of skeletal deformities from fractures/soft tissue damage/ruptures or replacement/resection of degenerated joints. Modern research is currently concentrating on innovative procedures to replenish/restore the human body close to its original/natural state [1, 2].

摘要

从出生到死亡,无数的肌肉骨骼疾病困扰着世界上绝大多数人。无数的病理疾病和创伤(急性和慢性)导致了不同的人类残疾,给医疗保健经济带来了巨大的损失。医学界一直在寻找新的方法来对抗与骨科相关的疾病。目前的直接目标是恢复解剖结构,然后最终恢复功能,希望提高生活质量(如果不能提高数量的话)。传统的方法包括手术矫正/重建骨骼畸形,如骨折/软组织损伤/破裂,或替换/切除退化的关节。现代研究目前正集中于创新的程序,以补充/恢复人体接近其原始/自然状态[1,2]。

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