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本文引用的文献

1
The 3D Spatial Autocorrelation of the Branching Fractal Vasculature.分支分形脉管系统的三维空间自相关
Acoustics (Basel). 2019 Jun;1(2):369-382. doi: 10.3390/acoustics1020020. Epub 2019 Apr 9.
2
Shapes and distributions of soft tissue scatterers.软组织散射体的形状和分布。
Phys Med Biol. 2019 Sep 5;64(17):175022. doi: 10.1088/1361-6560/ab2485.
3
Generalized poisson 3-D scatterer distributions.广义泊松三维散射体分布
IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Feb;56(2):410-4. doi: 10.1109/TUFFC.2009.1052.
4
Tissue characterization based on scatterer number density estimation.基于散射体数密度估计的组织特征分析。
IEEE Trans Ultrason Ferroelectr Freq Control. 1988;35(6):749-57. doi: 10.1109/58.9332.
5
Spectral characterization of tissues microstructure by ultrasounds: a stochastic approach.通过超声对组织微观结构进行光谱表征:一种随机方法。
IEEE Trans Ultrason Ferroelectr Freq Control. 1990;37(5):448-56. doi: 10.1109/58.105251.
6
Generation of non-Rayleigh speckle distributions using marked regularity models.使用标记规则模型生成非瑞利散斑分布。
IEEE Trans Ultrason Ferroelectr Freq Control. 1999;46(4):867-74. doi: 10.1109/58.775652.
7
Effect of red cell clustering and anisotropy on ultrasound blood backscatter: a Monte Carlo study.红细胞聚集和各向异性对超声血液反向散射的影响:一项蒙特卡洛研究。
IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Jan;52(1):94-103.
8
Simulation of ultrasound backscattering by red cell aggregates: effect of shear rate and anisotropy.红细胞聚集体超声背向散射的模拟:剪切速率和各向异性的影响
Biophys J. 2002 Apr;82(4):1696-710. doi: 10.1016/S0006-3495(02)75522-7.
9
A point process approach to assess the frequency dependence of ultrasound backscattering by aggregating red blood cells.一种通过聚集红细胞来评估超声背向散射频率依赖性的点过程方法。
J Acoust Soc Am. 2001 Dec;110(6):3252-62. doi: 10.1121/1.1419092.
10
On modeling biomedical ultrasound RF echoes using a power-law shot-noise model.关于使用幂律散粒噪声模型对生物医学超声射频回波进行建模。
IEEE Trans Ultrason Ferroelectr Freq Control. 2001 Jul;48(4):953-68. doi: 10.1109/58.935712.

分形分支血管后向散射的一阶统计量。

The first order statistics of backscatter from the fractal branching vasculature.

机构信息

Department of Electrical and Computer Engineering, University of Rochester, Rochester, New York 14627, USA.

出版信息

J Acoust Soc Am. 2019 Nov;146(5):3318. doi: 10.1121/1.5132934.

DOI:10.1121/1.5132934
PMID:31795650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6853797/
Abstract

The issue of speckle statistics from ultrasound images of soft tissues such as the liver has a long and rich history. A number of theoretical distributions, some related to random scatterers or fades in optics and radar, have been formulated for pulse-echo interference patterns. This work proposes an alternative framework in which the dominant echoes are presumed to result from Born scattering from fluid-filled vessels that permeate the tissue parenchyma. These are modeled as a branching, fractal, self-similar, multiscale collection of cylindrical scatterers governed by a power law distribution relating to the number of branches at each radius. A deterministic accounting of the echo envelopes across the scales from small to large is undertaken, leading to a closed form theoretical formula for the histogram of the envelope of the echoes. The normalized histogram is found to be related to the classical Burr distribution, with the key power law parameter directly related to that of the number density of vessels vs diameter, frequently reported in the range of 2 to 4. Examples are given from liver scans to demonstrate the applicability of the theory.

摘要

软组织(如肝脏)超声图像的散斑统计问题有着悠久而丰富的历史。已经为脉冲回波干扰模式制定了一些理论分布,其中一些与光学和雷达中的随机散射体或衰落有关。这项工作提出了一种替代框架,其中假定主要回波是由充满充满组织实质的流体的血管的玻恩散射产生的。这些被建模为一个分支的、分形的、自相似的、多尺度的圆柱形散射体集合,由与每个半径处的分支数相关的幂律分布来控制。对从小尺度到大尺度的回波包络进行确定性的计算,从而得到回波包络的直方图的封闭形式理论公式。归一化的直方图被发现与经典的 Burr 分布有关,关键的幂律参数与血管的数量密度与直径的关系直接相关,通常报告的范围在 2 到 4 之间。从肝脏扫描中给出了一些示例,以证明该理论的适用性。