Wilson Sylia, Haroian Kevin, Iacono William G, Krueger Robert F, Lee James J, Luciana Monica, Malone Stephen M, McGue Matt, Roisman Glenn I, Vrieze Scott
Institute of Child Development, University of Minnesota, Minneapolis, MN, USA.
Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
Twin Res Hum Genet. 2019 Dec;22(6):746-752. doi: 10.1017/thg.2019.107. Epub 2019 Dec 3.
The Minnesota Center for Twin and Family Research (MCTFR) comprises multiple longitudinal, community-representative investigations of twin and adoptive families that focus on psychological adjustment, personality, cognitive ability and brain function, with a special emphasis on substance use and related psychopathology. The MCTFR includes the Minnesota Twin Registry (MTR), a cohort of twins who have completed assessments in middle and older adulthood; the Minnesota Twin Family Study (MTFS) of twins assessed from childhood and adolescence into middle adulthood; the Enrichment Study (ES) of twins oversampled for high risk for substance-use disorders assessed from childhood into young adulthood; the Adolescent Brain (AdBrain) study, a neuroimaging study of adolescent twins; and the Siblings Interaction and Behavior Study (SIBS), a study of adoptive and nonadoptive families assessed from adolescence into young adulthood. Here we provide a brief overview of key features of these established studies and describe new MCTFR investigations that follow up and expand upon existing studies or recruit and assess new samples, including the MTR Study of Relationships, Personality, and Health (MTR-RPH); the Colorado-Minnesota (COMN) Marijuana Study; the Adolescent Brain Cognitive Development (ABCD) study; the Colorado Online Twins (CoTwins) study and the Children of Twins (CoT) study.
明尼苏达双胞胎与家庭研究中心（MCTFR）包括多项针对双胞胎和收养家庭的纵向、具有社区代表性的调查，这些调查聚焦于心理调适、人格、认知能力和脑功能，特别强调物质使用及相关精神病理学。MCTFR包括明尼苏达双胞胎登记处（MTR），这是一组在中年及老年期完成评估的双胞胎队列；从童年和青春期到中年期接受评估的双胞胎的明尼苏达双胞胎家庭研究（MTFS）；从童年到青年期对物质使用障碍高风险双胞胎进行过采样的富集研究（ES）；青少年大脑（AdBrain）研究，一项针对青少年双胞胎的神经影像学研究；以及兄弟姐妹互动与行为研究（SIBS），一项从青春期到青年期对收养家庭和非收养家庭进行评估的研究。在此，我们简要概述这些既定研究的关键特征，并描述MCTFR的新调查，这些新调查对现有研究进行跟进和扩展，或招募和评估新样本，包括关系、人格与健康的MTR研究（MTR-RPH）；科罗拉多-明尼苏达（COMN）大麻研究；青少年大脑认知发展（ABCD）研究；科罗拉多在线双胞胎（CoTwins）研究和双胞胎子女（CoT）研究。
